1-(2-Methoxy-5-(trifluoromethoxy)phenyl)ethanol CAS 468074-91-1
| CAS No. | 468074-91-1 |
| Molecular Formula | C10H11F3O3 |
| Molecular Weight | 236.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(2-Methoxy-5-(trifluoromethoxy)phenyl)ethanol (CAS 468074-91-1), molecular formula C10H11F3O3 and molecular weight 236.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(2-Methoxy-5-(trifluoromethoxy)phenyl)ethanol (C10H11F3O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(2-Methoxy-5-(trifluoromethoxy)phenyl)ethanol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H11F3O3 |
| Molecular Weight | 236.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Methoxy Standards
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Recommended Standards
- (6-Bromo-hexyl)-diethyl-amine (CAS 74509-66-3)
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- 2-(1-(3-(Trifluoromethyl)phenyl)ethylidene)malononitrile (CAS 866143-71-7)
- 2-(8-chloro-3,4-dihydro-2H-1-benzopyran-6-yl)acetonitrile (CAS 1803599-62-3)
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- 2-Methoxy-5-(2-(pyrrolidine-3-carbonyl)phenyl)nicotinic acid (CAS 1261958-09-1)
- 2-Bromo-6-iodo-4-methylaniline (CAS 289038-12-6)
- Salbutamol Impurity M HCl (CAS 18910-70-8（free base）)
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