4-chloro-N-[(4-methylphenyl)methylidene]benzene-1-sulfonamide CAS 468080-03-7
| CAS No. | 468080-03-7 |
| Molecular Formula | C14H12ClNO2S |
| Molecular Weight | 293.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-chloro-N-[(4-methylphenyl)methylidene]benzene-1-sulfonamide.
4-chloro-N-[(4-methylphenyl)methylidene]benzene-1-sulfonamide (CAS 468080-03-7) is a high-purity analytical reference standard with the molecular formula C14H12ClNO2S and a molecular weight of 293.77 g/mol.
The molecular framework of 4-chloro-N-[(4-methylphenyl)methylidene]benzene-1-sulfonamide (C14H12ClNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-chloro-N-[(4-methylphenyl)methylidene]benzene-1-sulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H12ClNO2S |
| Molecular Weight | 293.77 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related chloro Standards
- 5-Chloro-2-methoxy-N-(2-methoxyethyl)-4-methylbenzenesulfonamide (CAS 1087640-21-8)
- 7-Chloro-4-[(thiophen-2-yl)methyl]-2,3,4,5-tetrahydro-1,4-benzoxazepin-3-one (CAS 1341001-70-4)
- 1-(3-((6-Chloro-2-(methylthio)pyrimidin-4-yl)amino)phenyl)ethan-1-one (CAS 1426935-68-3)
- 11-Chloro-6-methyl-6,11-dihydrodibenzo[c,f][1,2]thiazepine 5,5-dioxide (CAS 26638-64-2)
- 2-Chloro-7-(methoxymethoxy)-10H-phenothiazine (CAS 62835-54-5)
- 3-Chloro-5-[(4-methoxyphenethyl)amino]-4-isothiazolecarbonitrile (CAS 866009-34-9)
- 5-Chloro-2-(methylthio)-N-(p-tolyl)pyrimidine-4-carboxamide (CAS 306958-67-8)
- 5-Chloro-N-methyl-2-(methylthio)-N-phenylpyrimidine-4-carboxamide (CAS 838817-68-8)
Recommended Standards
- 2-Chlorobenzyl 2-(methylthio)nicotinate (CAS 721910-30-1)
- 9-Ethyl-9h-carbazole-3-sulfonyl chloride (CAS 24525-01-7)
- 2-[5-(chloromethyl)-3-oxo-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-4-yl]acetonitrile (CAS 731795-75-8)
- Benzenesulfonamide, N-[(4-chlorophenyl)methylene]-4-methyl-, [N(E)]- (CAS 357417-22-2)
- (2-Bromo-6-(sec-butyl)pyridin-4-yl)boronic acid (CAS 2225152-29-2)
- 4-[(3-fluorophenyl)methylidene]piperidine hydrochloride (CAS 183950-18-7)
- 3-Amino-3-deoxyglucose (CAS 576-44-3)
- 4-(Hexyloxy)-3-methoxybenzonitrile (CAS 185980-63-6)
- (2R)-1-aminopent-4-yn-2-ol hydrochloride (CAS 1807939-91-8)
- 2-(Acridin-9-ylamino)ethanol (CAS 4665-56-9)
- 4-(2-Ethylphenoxy)-2-(trifluoromethyl)aniline (CAS 946698-09-5)
- 1-(3-(5-Oxo-1-phenyl-2-thioxoimidazolidin-4-yl)propyl)guanidine (CAS 4405-04-3)
- [(1R,8S,9R)-bicyclo[6.1.0]non-4-yn-9-yl]methyl N-[(2-{2-[({bis[14-({[(1S)-1-{[(1S)-1-({4-[({[(10S,23S)-10-ethyl-18-fluoro-10-hydroxy-19-methyl-5,9-dioxo-8-oxa-4,15-diazahexacyclo[14.7.1.0²,¹⁴.0⁴,¹³.0⁶,¹¹.0²⁰,²⁴]tetracosa-1,6(11),12,14,16,18,20(24)-heptaen-23-yl]carbamoyl}oxy)methyl]phenyl}carbamoyl)ethyl]carbamoyl}-2-methylpropyl]carbamoyl}oxy)-3,6,9,12-tetraoxatetradecan-1-yl]sulfamoyl}carbamoyl)oxy]ethoxy}ethyl)sulfamoyl]carbamate (CAS 2765424-51-7)
- ([D2]Gly4)-Cholecystokinin Octapeptide (sulfated) ammonium salt (CAS 1926163-74-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com