2-(2,3,5-Trichlorophenyl)acetonitrile CAS 4681-16-7
| CAS No. | 4681-16-7 |
| Molecular Formula | C8H4Cl3N |
| Molecular Weight | 220.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(2,3,5-Trichlorophenyl)acetonitrile (C8H4Cl3N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 2-(2,3,5-Trichlorophenyl)acetonitrile (CAS 4681-16-7), a certified reference material (molecular formula C8H4Cl3N, MW 220.48 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(2,3,5-Trichlorophenyl)acetonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H4Cl3N |
| Molecular Weight | 220.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Trichlorophenyl Standards
- 2-(3,4,5-Trichlorophenyl)acetonitrile (CAS 139256-46-5)
- 2-(2,4,5-Trichlorophenyl)acetonitrile (CAS 2903-62-0)
- 2-(2,4,6-Trichlorophenyl)acetonitrile (CAS 72017-35-7)
- 2,4,6-Trichlorophenyl Isocyanate (CAS 2505-31-9)
- (2,4,6-trichlorophenyl)methanol 2 4 6-TRICHLOROBENZYL ALCOHOL 97 217479-60-2 (CAS 217479-60-2)
- 1-(2,3,4-Trichlorophenyl)ethanone (CAS 13608-87-2)
- 1-(2,4,6-Trichlorophenyl)ethanone (CAS 52120-00-0)
- 1-(3,4,5-Trichlorophenyl)ethanone (CAS 35981-65-8)
Recommended Standards
- 2-Chloro-2-(2,6-dichlorophenyl)acetonitrile (CAS 1247531-20-9)
- 2-(Trichloromethyl)benzonitrile (CAS 2635-68-9)
- 2-Chloro-2-(2,3-dichlorophenyl)acetonitrile (CAS 1247048-13-0)
- 2,5,6-Trichloro-1H-indole (CAS 286949-65-3)
- 3-(4-Fluorophenyl)-4-methylaniline (CAS 1175834-34-0)
- 1-(5-Methylfuran-2-yl)-N-((tetrahydrofuran-2-yl)methyl)ethan-1-amine (CAS 1021104-30-2)
- 3-(2-Methylpyridin-1-ium-1-yl)propane-1-sulfonate (CAS 56405-61-9)
- 2-Chloro-N-((4-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methyl)benzenesulfonamide (CAS 866018-72-6)
- 4-Bromo-N-(1-(2-methoxyethyl)-1,2,3,4-tetrahydroquinolin-7-yl)benzamide (CAS 1172394-45-4)
- N-Allyl-N-methyl-N-(2-methylallyl)butan-1-aminium bromide (CAS 6045-23-4)
- 2-(8-Fluoro-2-methyl-4-oxoquinolin-1(4H)-yl)acetic acid (CAS 1083197-24-3)
- 2,2-Difluoro-N-((1-methyl-1H-imidazol-5-yl)methyl)ethan-1-amine (CAS 1551863-96-7)
- 2-(3-Methylbutoxy)acetic acid (CAS 68298-29-3)
- Protein Kinase C (alpha) Peptide (CAS 159939-84-1)
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