3,5-Bis(methoxycarbonyl)phenylisocyanate CAS 46828-05-1
| CAS No. | 46828-05-1 |
| Molecular Formula | C11H9NO5 |
| Molecular Weight | 235.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3,5-Bis(methoxycarbonyl)phenylisocyanate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3,5-Bis(methoxycarbonyl)phenylisocyanate (CAS 46828-05-1), molecular formula C11H9NO5 and molecular weight 235.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3,5-Bis(methoxycarbonyl)phenylisocyanate (C11H9NO5) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H9NO5 |
| Molecular Weight | 235.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1970 |
| Nitrogen Atoms | 1 |
Related Bis Standards
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Recommended Standards
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- 4,4-Dimethyl-6-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride (CAS 1203686-10-5)
- 5-Amino-N-tert-butyl-2-fluorobenzene-1-sulfonamide (CAS 1094822-19-1)
- 2-(3-Methylbenzo[b]thiophen-2-yl)acetic acid (CAS 1505-52-8)
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