(2'-(Trifluoromethyl)-[1,1'-biphenyl]-4-yl)methanamine CAS 472964-20-8

Purity 97%+In StockPharmaceutical Standards
CAS No.472964-20-8
Molecular FormulaC14H12F3N
Molecular Weight251.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2'-(Trifluoromethyl)-[1,1'-biphenyl]-4-yl)methanamine CAS 472964-20-8 chemical structure

Description

The occurrence of (2'-(Trifluoromethyl)-[1,1'-biphenyl]-4-yl)methanamine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies (2'-(Trifluoromethyl)-[1,1'-biphenyl]-4-yl)methanamine (CAS 472964-20-8), a certified reference material (molecular formula C14H12F3N, MW 251.25 g/mol) for analytical method development and quality control.

The molecular framework of (2'-(Trifluoromethyl)-[1,1'-biphenyl]-4-yl)methanamine (C14H12F3N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures (2'-(Trifluoromethyl)-[1,1'-biphenyl]-4-yl)methanamine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC14H12F3N
Molecular Weight251.25 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms1

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