(4R)-4-(Difluoromethyl)-2,2-dimethyl-1,3-dioxolane CAS 474329-39-0
| CAS No. | 474329-39-0 |
| Molecular Formula | C6H10F2O2 |
| Molecular Weight | 152.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(4R)-4-(Difluoromethyl)-2,2-dimethyl-1,3-dioxolane (C6H10F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
(4R)-4-(Difluoromethyl)-2,2-dimethyl-1,3-dioxolane (CAS 474329-39-0) is a high-purity analytical reference standard with the molecular formula C6H10F2O2 and a molecular weight of 152.14 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (4R)-4-(Difluoromethyl)-2,2-dimethyl-1,3-dioxolane under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H10F2O2 |
| Molecular Weight | 152.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related R Standards
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Recommended Standards
- (4,4-Difluorotetrahydro-2H-pyran-2-yl)methanol (CAS 2791312-35-9)
- (3,3-Difluorotetrahydro-2H-pyran-2-yl)methanol (CAS 2718966-07-3)
- (1S,3s)-3-(2,2-difluoroethoxy)cyclobutan-1-ol (CAS 1989638-27-8)
- [3-(1,1-Difluoroethyl)oxetan-3-yl]methanol (CAS 2102412-02-0)
- 2-Bromo-1-(4-fluorophenoxy)-4-nitrobenzene (CAS 477856-83-0)
- [1,2,5]Oxadiazolo[3,4-b]pyrazine-5,6-diamine (CAS 202207-24-7)
- 5-Chloroquinoline-6-carbaldehyde (CAS 180421-64-1)
- N-(2-Ethylhexyl)-2-hydroxybenzamide (CAS 81957-23-5)
- (2R,4R)-2-(tert-Butyl)-3-(ethoxycarbonyl)-4-(indol-3-yl-methyl]-4-methyl-1,3-oxazolidin-5-one (CAS 170458-97-6)
- 3-(5-Chlorothiophen-2-yl)-6-hydrazinylpyridazine (CAS 75792-88-0)
- Sofosbuvir Impurity 105 (CAS 1946820-91-2)
- N-(2,3-dimethylquinoxalin-6-yl)-3-(trifluoromethyl)benzenesulfonamide (CAS 672950-09-3)
- 1-(3-(2,4-Dichlorophenyl)-5-methylisoxazol-4-yl)ethanone (CAS 169814-56-6)
- Tirzepatide Impurity 59 (CAS CATO-C4X-324059)
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