Spiro[furo[3,4-c]pyridine-3(1H),4'-piperidin]-1-one hydrochloride CAS 475152-16-0
| CAS No. | 475152-16-0 |
| Molecular Formula | C11H12N2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 240.69 g/mol gives Spiro[furo[3,4-c]pyridine-3(1H),4'-piperidin]-1-one hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Spiro[furo[3,4-c]pyridine-3(1H),4'-piperidin]-1-one hydrochloride (CAS 475152-16-0), molecular formula C11H12N2O2HCl and molecular weight 240.69 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Spiro[furo[3,4-c]pyridine-3(1H),4'-piperidin]-1-one hydrochloride (C11H12N2O2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Spiro[furo[3,4-c]pyridine-3(1H),4'-piperidin]-1-one hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H12N2O2 HCl |
| Molecular Weight | 240.69 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Spiro Standards
- 1h-Spiro[furo[3,4-c]pyridine-3,4'-piperidine] dihydrochloride (CAS 1017599-04-0)
- SPIRO[IMIDAZOLIDINE-4,1'-INDENE]-2,5-DIONE (CAS 102325-53-1)
- Spiro[adamantane-2,3'-indole]-2'-amine hydrochloride (CAS 1029986-95-5)
- 1'H-Spiro[piperidine-4,4'-quinolin]-2'(3'H)-one hydrochloride (CAS 1032143-27-3)
- spiro[7H-furo[3,4-b]pyridine-5,4'-piperidine] (CAS 1036408-86-2)
- Spiro[piperidine-4,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one hydrochloride (CAS 1038866-43-1)
- Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H)-one hydrochloride (CAS 1038866-44-2)
- Spiro[cyclopentane-1,1'-indene] (CAS 10408-80-7)
Recommended Standards
- methyl 3-(3,4-dimethoxyphenyl)-2-methyloxirane-2-carboxylate (CAS 13605-37-3)
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- 2-(4-Bromo-2-fluorophenoxy)benzaldehyde (CAS 338393-63-8)
- 1185020-84-1 Benzyl 4-(Bromophenyl)-ether-d4 (CAS 1185020-84-1)
- [(2-nitrophenyl)methyl](2,2,2-trifluoroethyl)amine hydrochloride (CAS 1171562-15-4)
- (3-(4-(Tert-butyl)phenyl)-1,2,4-oxadiazol-5-yl)methanol (CAS 2412729-97-4)
- 3-Chloro-2-{[(6-chloropyridin-3-yl)methyl]sulfanyl}-5-(trifluoromethyl)pyridine (CAS 478048-57-6)
- 2,6-Dimethylcarbonylphenyl 9-Acridinecarboxylate 4-NHS Ester (CAS 115853-72-0)
- n-(4-Ethylcyclohexyl)-3-(pyrrolidin-1-yl)aniline (CAS 1178166-75-0)
- Des-Pro31-Tirzepatide (CAS CATO-CPTD788943)
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