8-Bromo-6-methoxy-1,2,3,4-tetrahydroquinoline CAS 475159-35-4
| CAS No. | 475159-35-4 |
| Molecular Formula | C10H12BrNO |
| Molecular Weight | 242.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
8-Bromo-6-methoxy-1,2,3,4-tetrahydroquinoline (CAS 475159-35-4), molecular formula C10H12BrNO and molecular weight 242.11 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution, 8-Bromo-6-methoxy-1,2,3,4-tetrahydroquinoline is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 242.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H12BrNO |
| Molecular Weight | 242.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 8-Bromo-2,3,4,5-tetrahydrobenzo[b]oxepin-5-amine (CAS 1016734-79-4)
- 5-Bromo-2-(cyclopropylmethoxy)aniline (CAS 1019590-24-9)
- 7-Bromo-6-methoxy-1,2,3,4-tetrahydroquinoline (CAS 106103-37-1)
- 2-Bromo-1-(3-(dimethylamino)phenyl)ethanone (CAS 112598-92-2)
- 2-Bromo-5-(cyclopentyloxy)pyridine (CAS 1144110-16-6)
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Recommended Standards
- 8-Bromo-5-methoxy-1,2,3,4-tetrahydroisoquinoline (CAS 392660-50-3)
- N-(1-(2-bromophenyl)ethyl)acetamide (CAS 949912-53-2)
- 6-Bromo-2-methyl-1,2,3,4-tetrahydroquinolin-4-ol (CAS 736939-28-9)
- n-(1-(4-Bromophenyl)ethyl)acetamide (CAS 92520-16-6)
- 2-(Tert-butoxy)-6-methylaniline (CAS 1341474-55-2)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-((diphenyl(p-tolyl)methyl)amino)pentanoic acid (CAS 343770-23-0)
- 2-Amino-5-bromobenzothiazole (CAS 20358-03-6)
- N1,N1-Dimethyl-1-(pyridin-2-yl)ethane-1,2-diamine (CAS 933756-92-4)
- (R)-1-amino-2,3-dihydro-1H-indene-5-carbonitrile (CAS 903630-06-8)
- Ginsenoside Rg6 (CAS 147419-93-0)
- 4-(3-(3,4-Dichlorophenyl)ureido)-2-methylbenzene-1-sulfonyl chloride (CAS 677327-01-4)
- Clerodendrin (CAS 119738-57-7)
- 6-((4-Hydroxypiperidin-1-yl)sulfonyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 317329-46-7)
- Insulin Degludec Impurity 26 (CAS CATO-C4X-215726)
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