tert-Butyl 4-(5-fluoro-2-nitrophenyl)-piperazine-1-carboxylate CAS 475279-74-4
| CAS No. | 475279-74-4 |
| Molecular Formula | C15H20FN3O4 |
| Molecular Weight | 325.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of tert-Butyl 4-(5-fluoro-2-nitrophenyl)-piperazine-1-carboxylate is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
tert-Butyl 4-(5-fluoro-2-nitrophenyl)-piperazine-1-carboxylate (CAS 475279-74-4), molecular formula C15H20FN3O4 and molecular weight 325.34 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, tert-Butyl 4-(5-fluoro-2-nitrophenyl)-piperazine-1-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 325.34 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), tert-Butyl 4-(5-fluoro-2-nitrophenyl)-piperazine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H20FN3O4 |
| Molecular Weight | 325.34 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
- Tert-butyl 4-(4-fluoro-2-nitrophenyl)piperazine-1-carboxylate (CAS 874814-94-5)
- 61899-79-4 Acetamide, N-(2-(fluoromethyl)-3,4-dihydro-3-(2-methylphenyl)-4-oxo-6-quinazolinyl)- 5-25-15-00102 (Beilstein Handbook Reference) N-Acetylafloqualone BRN 0897461 N-(2-(Fluoromethyl)-3,4-dihydro-3-(2-methylphenyl)-4-oxo-6-quinazolinyl)acetamide (CAS 61899-79-4)
- tert-Butyl 4-(3-fluoro-4-nitrophenyl)piperazine-1-carboxylate (CAS 536977-31-8)
- Olaparib Impurity 111 (CAS 2415448-60-9)
- 3-(Methylamino)pyridazine-4-carbonitrile (CAS 1256268-95-7)
- 3-Butyl-5-(hydroxyamino)-1,6-dihydropyrazin-2(3H)-one (CAS 20855-70-3)
- 3-Phenyl-5,6-dihydro-4H-pyrrolo[1,2-c][1,2,3]triazole (CAS 40930-12-9)
- Forskolin G (CAS 473981-11-2)
- Potassium trifluoro(3-((3-nitrophenyl)amino)-3-oxopropyl)borate (CAS 1705578-38-6)
- 1-Ethyl-4-[(4-methoxybenzyl)amino]-3-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid (CAS 860785-53-1)
- N-(pyridin-4-yl)formamide (CAS 22236-91-5)
- 1-(4-Chlorobenzyl)-1h-imidazole-4-carboxylic acid (CAS 725234-31-1)
- Methyl 3-(chlorosulfonyl)-2,6-dimethoxybenzoate (CAS 1154160-17-4)
- Vialox Peptide(Pentapeptide-3) diacetate (CAS 725232-44-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com