2-(3-iodophenyl)imidazo[1,2-a]pyridine CAS 475992-42-8
| CAS No. | 475992-42-8 |
| Molecular Formula | C13H9IN2 |
| Molecular Weight | 320.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(3-iodophenyl)imidazo[1,2-a]pyridine (CAS 475992-42-8) is a high-purity analytical reference standard with the molecular formula C13H9IN2 and a molecular weight of 320.13 g/mol.
The molecular framework of 2-(3-iodophenyl)imidazo[1,2-a]pyridine (C13H9IN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(3-iodophenyl)imidazo[1,2-a]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H9IN2 |
| Molecular Weight | 320.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
Related iodophenyl Standards
- 2-(4-Iodophenyl)benzofuran (CAS 1439923-28-0)
- 2-(2-Iodophenyl)-1h-benzo[d]imidazole (CAS 24192-81-2)
- 2-(4-Iodophenyl)imidazo[1,2-a]pyridine (CAS 214958-27-7)
- 3-(2-Iodophenyl)benzofuran (CAS 452962-66-2)
- 1-(4-Iodophenyl)-2-(isopropylthio)ethan-1-one (CAS 1182904-44-4)
- n-(3-Iodophenyl)tetrahydro-2h-thiopyran-4-amine (CAS 1156599-90-4)
- n-(2-Iodophenyl)tetrahydro-2h-thiopyran-4-amine (CAS 1156989-25-1)
- n-(2-Iodophenyl)tetrahydro-2h-thiopyran-3-amine (CAS 1339671-36-1)
Recommended Standards
- 2-(3,4-Dichlorobenzoyl)isoindoline-1,3-dione (CAS 28394-56-1)
- 2-((2-Hydroxyethyl)amino)-N-(4-iodophenyl)acetamide (CAS 298215-09-5)
- 3-Iodo-2-phenylbenzofuran (CAS 246230-86-4)
- 1,6-Diamino-4-(3,4-dichlorophenyl)-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile (CAS 725699-99-0)
- 6-(4-Iodophenyl)hexanoic acid (CAS 256486-41-6)
- 2-Methyl-4-[(2-methylpentyl)oxy]aniline (CAS 946785-92-8)
- Denaverine hydrochloride (CAS 3321-06-0)
- 3-(2,3-Dihydro-1H-inden-5-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde (CAS 955976-62-2)
- (5-Chloro-6-(2-fluorophenyl)pyridin-3-yl)boronic acid (CAS 2225155-82-6)
- tert-Butyl (4-((4-methylpyrimidin-2-yl)amino)cyclohexyl)carbamate (CAS 1289388-33-5)
- 6-amino-3,10-dioxatricyclo[5.2.1.0^{1,5}]decan-4-one hydrochloride (CAS 2059927-75-0)
- 2-(Difluoromethyl)-3-iodo-6-methoxypyridin-4-amine (CAS 1804516-10-6)
- 5-methoxy-2,3,6,7-tetrahydro-1$l^{6},4-thiazepine-1,1-dione (CAS 2059937-84-5)
- Insulin Degludec Impurity 26 (CAS CATO-C4X-215726)
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