Roxatidine Impurity 46 CAS 4764-13-0
| CAS No. | 4764-13-0 |
| Molecular Formula | C12H17NO |
| Molecular Weight | 191.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Roxatidine Impurity 46 (CAS 4764-13-0, C12H17NO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Roxatidine Impurity 46 (C12H17NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 191.27 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Roxatidine Impurity 46 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H17NO |
| Molecular Weight | 191.27 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Roxatidine Standards
- Roxatidine Impurity 4 (CAS 73279-04-6)
- Roxatidine Impurity 45 (CAS 73152-41-7)
- Roxatidine Impurity 71 (CAS CATO-C4X-121371)
- Roxatidine Impurity 80 (CAS 853574-98-8)
- Roxatidine Impurity 49 (CAS 4530-44-3)
- Roxatidine Impurity 22 (CAS 72126-71-7)
- Roxatidine Impurity 55 (CAS 100841-00-7)
- Roxatidine Impurity 34 (CAS 15504-60-6)
Recommended Standards
- Rotigotine Impurity 33 (CAS CATO-C4X-192733)
- Benidipine Impurity 17 (CAS 14813-01-5)
- Aprepitant impurity 33 (CAS 599162-15-9)
- Paroxetine Impurity 25 (CAS CATO-C4X-103525)
- Cariprazine Impurity 41 (CAS 1957145-61-7)
- Moxifloxacin Impurity 91 (CAS 89-00-9)
- Landiolol Impurity 101 (CAS CATO-C4X-2621101)
- 1,4-Dibenzyl-2-(hydroxymethyl)piperazine (CAS 94437-04-4)
- (E)-3-(4-((4-fluorobenzyl)oxy)phenyl)acrylic acid (CAS 175136-19-3)
- Ethyl 4,5-dichloro-2-fluorophenylacetate (CAS 1805479-66-6)
- N-cyclopentyl-2-(N’-hydroxycarbamimidoyl)acetamide (CAS 926212-99-9)
- (5E)-3-Ethyl-5-{[5-nitro-2-(phenylsulfanyl)phenyl]methylidene}-2-sulfanylidene-1,3-thiazolidin-4-one (CAS 329079-73-4)
- 2-(5-Chloropyrimidin-4-yl)acetic acid (CAS 1260811-07-1)
- Semaglutide Impurity 143 (CAS CATO-C4X-2226143)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com