N-(4-Chloro-2-methoxy-5-methylphenyl)-2-((4-(4-chlorophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide CAS 476483-99-5
| CAS No. | 476483-99-5 |
| Molecular Formula | C23H19Cl2N5O2S |
| Molecular Weight | 500.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(4-Chloro-2-methoxy-5-methylphenyl)-2-((4-(4-chlorophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide.
CATO supplies N-(4-Chloro-2-methoxy-5-methylphenyl)-2-((4-(4-chlorophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 476483-99-5), a certified reference material (molecular formula C23H19Cl2N5O2S, MW 500.40 g/mol) for analytical method development and quality control.
The molecular framework of N-(4-Chloro-2-methoxy-5-methylphenyl)-2-((4-(4-chlorophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (C23H19Cl2N5O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H19Cl2N5O2S |
| Molecular Weight | 500.40 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related N Standards
- N-(4-chloro-3-nitrophenyl)-2-((5-(4-chlorophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 443739-90-0)
- (R)-4-(2-((2-Chloro-4-fluorophenyl)amino)-5-methylpyrimidin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide (CAS 1680187-43-2)
- (E)-3-((2-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2-oxoethoxy)imino)-2-(4-chlorophenyl)propanenitrile (CAS 400076-75-7)
- N-(3-chloro-4-methoxyphenyl)-2-((3-ethyl-4-oxo-7-(p-tolyl)-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1040632-87-8)
- N-(5-Chloro-2-methoxyphenyl)-2-{[3-ethyl-7-(4-methylphenyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide (CAS 1040651-81-7)
- N-(4-Chloro-2-methoxy-5-methylphenyl)-2-({3-ethyl-4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-2-yl}sulfanyl)acetamide (CAS 1040662-84-7)
- 2-chloro-4,6-bis(9,9-dimethyl-9H-fluoren-2yl)-1,3,5-Triazine (CAS 1459162-69-6)
- 2-(5-((3-(3-Chloro-4-ethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid (CAS 956958-57-9)
Recommended Standards
- Diethyl 1-(3,5-bis(trifluoromethyl)phenyl)-5-phenyl-1H-pyrazole-3,4-dicarboxylate (CAS 96722-93-9)
- N-(2-Benzenesulfonamidoethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide (CAS 338404-57-2)
- 3-((4-Bromophenyl)sulfonyl)-N-(m-tolyl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-amine (CAS 892749-88-1)
- N-(4-bromophenyl)-2-((3-cyano-4,6-diphenylpyridin-2-yl)thio)acetamide (CAS 299164-53-7)
- Benzyl piperidine-3-carboxylate (CAS 97231-90-8)
- 1-benzyl-3-(methylamino)pyrrolidine-2,5-dione (CAS 1375471-50-3)
- (2S,5R)-5-Ethylpyrrolidine-2-carboxamide (CAS 102734-97-4)
- 2,6-Dimethylpyrazine (CAS 108-50-9)
- 6-Bromo-3-methyl-1,2,3,4-tetrahydro-isoquinoline (CAS 886365-45-3)
- N-benzyl-N-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazol-2-amine (CAS 2096333-04-7)
- 6-(tert-Butyl)-2-isopropyl-3-methylpyrimidin-4(3H)-one (CAS 108168-95-2)
- Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-indene-1-carboxylate (CAS 1423700-47-3)
- 2-(pyridin-3-yloxy)benzoic acid (CAS 1094325-06-0)
- Tau Peptide (277-291) trifluoroacetate salt (CAS 330456-40-1)
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