2-Fluoro-4-(bromomethyl)benzoic acid CAS 477199-77-2
| CAS No. | 477199-77-2 |
| Molecular Formula | C8H6BrFO2 |
| Molecular Weight | 233.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 233.03 g/mol gives 2-Fluoro-4-(bromomethyl)benzoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Fluoro-4-(bromomethyl)benzoic acid (CAS 477199-77-2), molecular formula C8H6BrFO2 and molecular weight 233.03 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system, 2-Fluoro-4-(bromomethyl)benzoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 233.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Fluoro-4-(bromomethyl)benzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6BrFO2 |
| Molecular Weight | 233.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
Related Fluoro Standards
- (4-Fluoro-3-(methylsulfonamido)phenyl)boronic acid (CAS 1009303-57-4)
- (5-Fluoro-2-(n-methylsulfamoyl)phenyl)boronic acid (CAS 1218790-75-0)
- (3-Fluoro-4-(N-methylsulfamoyl)phenyl)boronic acid (CAS 1704095-91-9)
- (2-Fluoro-5-(N-methylsulfamoyl)phenyl)boronic acid (CAS 2563893-99-0)
- 5-Fluoro-2-(bromomethyl)benzoic acid (CAS 23990-40-1)
- 2-Fluoro-3,5-bis(trifluoromethyl)pyridine (CAS 119071-61-3)
- 2-Fluoro-4,5-bis(trifluoromethyl)pyridine (CAS 1204234-69-4)
- 2-Fluoro-3,4-bis(trifluoromethyl)pyridine (CAS 1204295-75-9)
Recommended Standards
- 2-Bromo-6-fluoro-4-methoxybenzaldehyde (CAS 856767-10-7)
- 3-(1-Bromo-2,2,2-trifluoroethyl)tetrahydrofuran (CAS 2137857-73-7)
- 2-Bromo-5-fluorophenyl acetic acid, 97% (CAS 739336-26-6)
- 3-(Bromomethyl)-4-fluorobenzoic acid (CAS 89540-20-5)
- 6-Bromo-2-(pyridin-4-yl)quinoline-4-carbonyl chloride (CAS 1203419-34-4)
- N-(2-(3-(4-Fluorophenyl)-6-oxopyridazin-1(6H)-yl)ethyl)-2,2-diphenylacetamide (CAS 921575-61-3)
- 3-Bromo-4-(methylthio)phenol (CAS 1243458-10-7)
- cis-4-Aminotetrahydro-2H-thiopyran 1-oxide hydrochloride (CAS 1418199-70-8)
- (S)-2-Amino-N-cyclopropyl-N-(3-methoxybenzyl)propanamide (CAS 1354006-67-9)
- 3-(4-Benzhydryl-1-piperazinyl)-N-ethyl-1-propanamine (CAS 1040692-49-6)
- Avasimibe (CAS 166518-60-1)
- Ethyl 7-oxo-9-azabicyclo[3.3.1]nonane-3-carboxylate (CAS 1215183-26-8)
- 2-(Benzo[d][1,3]dioxol-5-yl)benzofuran-3-amine (CAS 1269534-56-6)
- Peptide T (CAS 106362-32-7)
Why CATO?
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