3-(chloromethyl)-2-fluoro-pyridine;hydrochloride CAS 477207-34-4
| CAS No. | 477207-34-4 |
| Molecular Formula | C6H11ClFN |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(chloromethyl)-2-fluoro-pyridine;hydrochloride.
3-(chloromethyl)-2-fluoro-pyridine;hydrochloride (CAS 477207-34-4), molecular formula C6H11ClFNHCl and molecular weight 188.07 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to fluorine/chlorine substitution, 3-(chloromethyl)-2-fluoro-pyridine;hydrochloride is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 188.07 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H11ClFN HCl |
| Molecular Weight | 188.07 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related chloromethyl Standards
- 7-(Chloromethyl)-3-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-81-4)
- 7-(Chloromethyl)-2,3-dimethyl-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-82-5)
- 7-(Chloromethyl)-3-(4-chlorophenyl)-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-85-8)
- chloromethyl 2-ethoxy-2-methylpropanoate (CAS 1000296-74-1)
- 5-(chloromethyl)-N-(4-methylbenzyl)-1,3,4-thiadiazole-2-carboxamide (CAS 1000932-24-0)
- 5-(Chloromethyl)-7-ethoxy-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 1000932-47-7)
- 5-(chloromethyl)-N-(4-fluorobenzyl)-1,3,4-thiadiazole-2-carboxamide (CAS 1000932-60-4)
- 2-(Chloromethyl)-5,6-diphenylfuro[2,3-d]pyrimidin-4-amine (CAS 1000933-67-4)
Recommended Standards
- tert-Butyl 2-(6-(methylamino)pyridin-3-yl)pyrrolidine-1-carboxylate (CAS 1352516-55-2)
- N-Acetyl-3-(4-(p-methoxyphenyl)piperazinyl)azetidine (CAS 223381-95-1)
- Rel-(2R,3R)-3-((tert-Butoxycarbonyl)amino)-2-hydroxy-3-(4-Methoxyphenyl)propanoic acid (CAS 1217648-00-4)
- 2-Chloro-N-(2,5-diethoxy-4-morpholinophenyl)propanamide hydrochloride (CAS 1172248-02-0)
- 2-Methoxy-4-[4-(trifluoromethyl)piperidin-1-yl]aniline (CAS 1416352-07-2)
- {[(3-methylphenyl)methyl]sulfanyl}methanimidamide (CAS 763905-22-2)
- (1R,5S,6s)-Benzyl 6-((tert-butoxycarbonyl)amino)-3-azabicyclo[3.1.0]hexane-3-carboxylate (CAS 146726-08-1)
- 3-Hydroxy-5,5-dimethyl-2-(((4-(naphthalen-2-yloxy)phenyl)imino)methyl)cyclohex-2-en-1-one (CAS 1020252-64-5)
- (2-Allylphenoxy)trimethylsilane (CAS 18042-43-8)
- Tirzepatide Impurity 15 (CAS CATO-C4X-324015)
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