Methyl 3-(isoquinolin-4-yl)acrylate CAS 477250-22-9
| CAS No. | 477250-22-9 |
| Molecular Formula | C13H11NO2 |
| Molecular Weight | 213.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 3-(isoquinolin-4-yl)acrylate (CAS 477250-22-9) is a high-purity analytical reference standard with the molecular formula C13H11NO2 and a molecular weight of 213.23 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Methyl 3-(isoquinolin-4-yl)acrylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 213.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 3-(isoquinolin-4-yl)acrylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H11NO2 |
| Molecular Weight | 213.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 1-(isoquinolin-1-yl)cyclopropane-1-carboxylic acid (CAS 1158917-75-9)
- (R)-1-(Isoquinolin-5-yl)pyrrolidin-3-amine (CAS 675602-50-3)
- 1-(Isoquinolin-5-yl)cyclopentan-1-amine (CAS 1342023-05-5)
- n-(1-(Isoquinolin-5-yl)ethyl)propan-1-amine (CAS 1310297-72-3)
- Isoquinolin-6-yl-acetic acid ethyl ester (CAS 1220040-16-3)
- Ethyl 2-(isoquinolin-7-yl)acetate (CAS 1261630-01-6)
- 2-(Isoquinolin-4-yl)-2-methylpropanoic acid (CAS 1341487-77-1)
- Methyl 2-(isoquinolin-5-yl)propanoate (CAS 1341696-45-4)
Recommended Standards
- Methyl 3-(3-pyridinyl)benzoate (CAS 79601-27-7)
- Methyl 3-(pyridin-2-yl)benzoate (CAS 98061-20-2)
- Methyl 2-Phenylisonicotinate (CAS 4634-14-4)
- Methyl 3-(quinolin-3-yl)acrylate (CAS 66417-78-5)
- 4-Methoxyindazole-6-carboxylic Acid (CAS 1167055-67-5)
- 2-(4-Acetylphenyl)-1,2-thiazolidine-1,1-dione (CAS 65873-97-4)
- 2-Mercapto-5,7-dimethylquinoline-3-carbonitrile (CAS 917750-53-9)
- 7-(1-Hydroxyethyl)isoindolin-1-one (CAS 773-65-9)
- 5-Bromo-N-cyclopropyl-2-fluoroaniline (CAS 1533902-45-2)
- 2,6-Difluoro-4-(trifluoromethyl)phenylboronic acid (CAS 2250114-85-1)
- Pyrene-4,5,9,10-tetraone (CAS 14727-71-0)
- 2-(3-Methoxy-4-nitro-1h-pyrazol-1-yl)acetohydrazide (CAS 512809-30-2)
- 2-3-4-6-Tetra-O-pivaloyl-β-D-galactopyranosyl amine (CAS 108342-87-6)
- Semaglutide impurity 96 (CAS CATO-C4X-222696)
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