3-((3-Fluoro-4-methylphenyl)amino)-1-(naphthalen-2-yl)propan-1-ol CAS 477320-39-1

Purity 97%+In StockPharmaceutical Standards
CAS No.477320-39-1
Molecular FormulaC20H20FNO
Molecular Weight309.38 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-((3-Fluoro-4-methylphenyl)amino)-1-(naphthalen-2-yl)propan-1-ol CAS 477320-39-1 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

3-((3-Fluoro-4-methylphenyl)amino)-1-(naphthalen-2-yl)propan-1-ol (CAS 477320-39-1) is a high-purity analytical reference standard with the molecular formula C20H20FNO and a molecular weight of 309.38 g/mol.

3-((3-Fluoro-4-methylphenyl)amino)-1-(naphthalen-2-yl)propan-1-ol (C20H20FNO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC20H20FNO
Molecular Weight309.38 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms1

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