1-(Benzo[d][1,3]dioxol-5-yl)-3-((4-fluorophenyl)amino)propan-1-one CAS 477320-48-2
| CAS No. | 477320-48-2 |
| Molecular Formula | C16H14FNO3 |
| Molecular Weight | 287.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(Benzo[d][1,3]dioxol-5-yl)-3-((4-fluorophenyl)amino)propan-1-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(Benzo[d][1,3]dioxol-5-yl)-3-((4-fluorophenyl)amino)propan-1-one (CAS 477320-48-2), molecular formula C16H14FNO3 and molecular weight 287.29 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(Benzo[d][1,3]dioxol-5-yl)-3-((4-fluorophenyl)amino)propan-1-one (C16H14FNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(Benzo[d][1,3]dioxol-5-yl)-3-((4-fluorophenyl)amino)propan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H14FNO3 |
| Molecular Weight | 287.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Benzo Standards
- 3-(Benzo[d][1,3]dioxol-5-ylamino)-1-(4-fluorophenyl)propan-1-one (CAS 477333-88-3)
- 2-((Benzo[d][1,3]dioxol-5-ylimino)methyl)-3-hydroxy-5,5-dimethylcyclohex-2-en-1-one (CAS 202459-40-3)
- 3-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-3-oxopropanenitrile (CAS 546116-57-8)
- 3-(Benzo[d][1,3]dioxol-5-yl)-N-((3-methyl-1,2,4-oxadiazol-5-yl)methyl)acrylamide (CAS 1226487-82-6)
- N-(Benzo[d][1,3]dioxol-5-yl)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-2-carboxamide (CAS 1448132-50-0)
- 2-(1H-benzo[d][1,2,3]triazol-1-yl)-1-(naphthalen-2-yl)ethan-1-one (CAS 124041-72-1)
- 2-(Benzo[1,2,5]thiadiazole-4-sulfonylamino)-propionic acid (CAS 1396966-20-3)
- 3-(Benzo[c][1,2,5]thiadiazole-4-sulfonamido)propanoic acid (CAS 405279-59-6)
Recommended Standards
- 1-(5-Carboxythiophen-2-yl)-1H-indole-5-carboxylic acid (CAS 93104-74-6)
- 1-(Phenylsulfonyl)indoline-2,3-dione (CAS 58836-98-9)
- 1-(4-Fluorophenyl)-2-(2-(isopropylamino)pyrimidin-4-yl)ethane-1,2-dione (CAS 876521-37-8)
- 1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl 2-thiopheneacetate (CAS 752204-15-2)
- (2R,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid (CAS 145513-91-3)
- 1-[(4-Methylphenyl)sulfonyl]azetidin-3-yl 4-methylbenzenesulfonate (CAS 17358-66-6)
- 5-Amino-2-fluoro-n-methylbenzene-1-sulfonamide (CAS 1094887-98-5)
- 5-Bromo-2-((2-chlorobenzyl)oxy)benzonitrile (CAS 929450-83-9)
- 2-[Butyl(methyl)amino]isonicotinic acid (CAS 1019349-74-6)
- (4-Bromophenyl)(3,5-dichlorophenyl)methanol (CAS 1283678-14-7)
- Fmoc-Cit-PAB-OH (CAS 870487-04-0)
- 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)pyrrolidine hydrochloride (CAS 2096332-19-1)
- Ethyl 3-(4-(benzyloxy)phenyl)propanoate (CAS 186895-45-4)
- Insulin Degludec Impurity 24 (CAS CATO-C4X-215724)
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