2-((4-(4-Bromophenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide CAS 477329-24-1
| CAS No. | 477329-24-1 |
| Molecular Formula | C23H18BrN5O3S |
| Molecular Weight | 524.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((4-(4-Bromophenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide.
2-((4-(4-Bromophenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide (CAS 477329-24-1), molecular formula C23H18BrN5O3S and molecular weight 524.39 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution, 2-((4-(4-Bromophenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 524.39 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H18BrN5O3S |
| Molecular Weight | 524.39 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Bromophenyl Standards
- 2-((4-(4-Bromophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide (CAS 477329-83-2)
- Methyl 4-(2-((4-(4-bromophenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamido)benzoate (CAS 477329-64-9)
- (Z)-[(4-Bromophenyl)[2-(4-chlorophenyl)cyclopropyl]methylidene]amino 3,4-dichlorobenzoate (CAS 338415-64-8)
- Methyl 4-(2-((5-(2-bromophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamido)benzoate (CAS 332934-88-0)
- (5-((4-Bromophenyl)sulfonyl)-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl 2-methylbenzoate (CAS 318289-22-4)
- 3-(4-Bromophenyl)-2-((2-oxo-2-(p-tolyl)ethyl)thio)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one (CAS 476484-19-2)
- 1-(1-(4-Bromophenyl)ethyl)-4-((tert-butyldiphenylsilyl)oxy)piperidine (CAS 1704096-96-7)
- 2-[(4-Bromophenyl)sulfanyl]-4-(2,4-dichlorophenyl)-6-(4-methylphenyl)pyridine-3-carbonitrile (CAS 341964-90-7)
Recommended Standards
- Triethoxy[4,4-bis(trifluoromethyl)-5,5,6,6,7,7,7-heptafluoroheptyl]silane (CAS 130676-81-2)
- DNMB-cAMP (CAS 92313-25-2)
- 4-Bromo-N'-(2-((5-(4-hydroxyphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetyl)benzohydrazide (CAS 332910-55-1)
- Fosfomycin Impurity 25 (CAS CATO-C4X-131625)
- 4-(4-Bromophenyl)-2,5-dimethylpyrazol-3-amine (CAS 1152678-01-7)
- 2-(2-Mercapto-1H-benzo[d]imidazol-1-yl)-1-(piperidin-1-yl)ethanone (CAS 917749-43-0)
- 38487-86-4 2-Amino-4-chlorobenzonitrile Benzonitrile, 2-amino-4-chloro- 5-Chloro-2-cyanoaniline EINECS 253-967-8 (CAS 38487-86-4)
- N-(2-((tert-Butyldimethylsilyl)oxy)ethyl)-3,5-dimethoxyaniline (CAS 1346245-09-7)
- Methyl 3-thioxo-2,3-dihydro-[1,2,4]triazolo[4,3-b]pyridazine-6-carboxylate (CAS 1393352-88-9)
- 2-[(5-carbamoylpyridin-2-yl)amino]acetic acid (CAS 1016864-70-2)
- 3-Ethyl-8-(pyrrolidin-3-yl)quinoline (CAS 695185-35-4)
- 2-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-imidazole hydrochloride (CAS 1955540-65-4)
- imidazo[1,2-a]pyrimidine-2-carbaldehyde (CAS 143982-40-5)
- Glucagon Monohydrochloride (CAS 28270-04-4)
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