2-((4-(4-Ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-1-(4-methoxyphenyl)ethanone CAS 477329-43-4
| CAS No. | 477329-43-4 |
| Molecular Formula | C24H22N4O3S |
| Molecular Weight | 446.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-((4-(4-Ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-1-(4-methoxyphenyl)ethanone is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-((4-(4-Ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-1-(4-methoxyphenyl)ethanone (CAS 477329-43-4), molecular formula C24H22N4O3S and molecular weight 446.52 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-((4-(4-Ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-1-(4-methoxyphenyl)ethanone (C24H22N4O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 446.52 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-((4-(4-Ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-1-(4-methoxyphenyl)ethanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H22N4O3S |
| Molecular Weight | 446.52 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Ethoxyphenyl Standards
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- N-[3-(4-Ethoxyphenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl]-1-[3-(piperidin-4-yl)propyl]-1H-pyrazol-4-amine (CAS 1448694-02-7)
- 3-(4-Ethoxyphenyl)-N-(1-(3-(piperidin-4-yl)propyl)-1H-pyrazol-3-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine (CAS 1956330-99-6)
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- N-(4-Ethoxyphenyl)-2-((3-ethyl-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 333318-93-7)
Recommended Standards
- (E)-N'-((5-(3-methoxyphenyl)-1H-pyrazol-4-yl)methylene)-3-((4-methylbenzyl)oxy)thiophene-2-carbohydrazide (CAS 477712-50-8)
- 2-((4-Allyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-(benzyloxy)phenyl)acetamide (CAS 573698-19-8)
- 3-[2-(3-Benzothiazol-6-yl-4-oxo-2-thioxo-thiazolidin-5-ylidene)-acetyl]-1H-indole-5-carbonitrile (CAS 1380572-37-1)
- 2-({4-[(4-Ethoxyanilino)sulfonyl]anilino}carbonyl)cyclohexanecarboxylic acid (CAS 543695-34-7)
- Ethyl 2-chloro-2-[2-(2,4-difluorophenyl)hydrazin-1-ylidene]acetate (CAS 1264087-24-2)
- 1,5-dioxaspiro[2.3]hexane (CAS 15791-59-0)
- Ethyl 4-(1,4-diazepan-1-yl)benzoate (CAS 234081-75-5)
- n-(3-Aminophenyl)nicotinamide (CAS 63556-12-7)
- 1-(4-amino-2-methylquinolin-3-yl)ethan-1-one (CAS 71993-15-2)
- 2-Bromo-5-(prop-2-yn-1-yl)thiophene (CAS 1352564-61-4)
- Dapagliflozin impurity 218 (CAS 3063007-40-6)
- 7-Tert-butyl-2-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-5-carboxylic acid (CAS 887672-46-0)
- 3-Bromo-5-(2-ethoxycarbonylbenzoyl)pyridine (CAS 898771-80-7)
- 30003-72-6 insulin chain b oxidized (CAS 30003-72-6)
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