4-(4-Chlorobenzoyl)-5-(4-chlorophenyl)-3-hydroxy-1-(6-methoxybenzo[d]thiazol-2-yl)-1H-pyrrol-2(5H)-one CAS 477333-51-0
| CAS No. | 477333-51-0 |
| Molecular Formula | C25H16Cl2N2O4S |
| Molecular Weight | 511.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(4-Chlorobenzoyl)-5-(4-chlorophenyl)-3-hydroxy-1-(6-methoxybenzo[d]thiazol-2-yl)-1H-pyrrol-2(5H)-one is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(4-Chlorobenzoyl)-5-(4-chlorophenyl)-3-hydroxy-1-(6-methoxybenzo[d]thiazol-2-yl)-1H-pyrrol-2(5H)-one (CAS 477333-51-0) is a high-purity analytical reference standard with the molecular formula C25H16Cl2N2O4S and a molecular weight of 511.38 g/mol.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 4-(4-Chlorobenzoyl)-5-(4-chlorophenyl)-3-hydroxy-1-(6-methoxybenzo[d]thiazol-2-yl)-1H-pyrrol-2(5H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 511.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H16Cl2N2O4S |
| Molecular Weight | 511.38 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorobenzoyl Standards
- Ethyl 3-{[2-(4-chlorobenzoyl)-1-benzofuran-3-yl]methoxy}pyrido[1,2-a]indole-10-carboxylate (CAS 339020-42-7)
- 1-(3-Chlorobenzoyl)-4-(4-chlorophenyl)-5-{2'-fluoro-4'-propyl-[1,1'-biphenyl]-4-yl}-1H-pyrazole (CAS 477762-88-2)
- 2-(4-Chlorobenzoyl)-3-({[3-(trifluoromethyl)phenyl]methanesulfonyl}methyl)-1-benzofuran (CAS 338424-36-5)
- 2-(4-Chlorobenzoyl)-3-[(2,4-dichlorobenzenesulfonyl)methyl]-1-benzofuran (CAS 338411-58-8)
- 2-(4-Chlorobenzoyl)-3-{[3-(trifluoromethyl)benzenesulfonyl]methyl}-1-benzofuran (CAS 338411-53-3)
- 4-(4-Chlorobenzoyl)-3-hydroxy-1-(6-methoxybenzo[d]thiazol-2-yl)-5-phenyl-1H-pyrrol-2(5H)-one (CAS 477333-34-9)
- (R)-2-(2-(1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetamido)-3-(methylthio)propanoic acid (CAS 87270-38-0)
- ethyl 2-[(2-chlorobenzoyl)amino]-2-(diisopropoxyphosphoryl)-3,3,3-trifluoropropanoate (CAS 340032-46-4)
Recommended Standards
- PPADS Tetrasodium (CAS 149017-66-3)
- Mal-PEG4-PFP ester (CAS 1415800-42-8)
- Methyl 2-(2-(2,4-dichlorophenoxy)acetamido)-5-((2-fluorophenyl)carbamoyl)-4-methylthiophene-3-carboxylate (CAS 335408-44-1)
- 2-((4-(4-Bromophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-1-(2,5-dimethoxyphenyl)ethanone (CAS 477329-10-5)
- 3-(4-Amino-2-methoxyphenyl)-1,3-oxazolidin-2-one (CAS 31847-25-3)
- 2-(pyridin-4-yl)-1,3-thiazole-5-carbaldehyde hydrochloride (CAS 1909327-51-0)
- 2-Chloro-N-(2-(dimethylamino)cyclohexyl)-N-methylacetamide (CAS 1353986-04-5)
- 3-Amino-3-(1H-indol-3-yl)propanoic acid (CAS 5814-94-8)
- (3α,5α,11α)-3,11-Dihydroxypregnan-20-one (CAS 38398-44-6)
- Olprinone Impurity 16 (CAS CATO-C4X-204316)
- 3,6-Dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one (CAS 6291-55-0)
- 20-Bromoicosan-1-ol (CAS 92002-48-7)
- 2-Methylpentanedial (CAS 7420-87-3)
- Semaglutide impurity 71 (CAS CATO-C4X-222671)
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