N-(3-chloro-4-methylphenyl)-2-(4-(2,4-dimethylphenyl)piperazin-1-yl)acetamide CAS 477333-96-3

Purity 97%+In StockPharmaceutical Standards
CAS No.477333-96-3
Molecular FormulaC21H26ClN3O
Molecular Weight371.90 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(3-chloro-4-methylphenyl)-2-(4-(2,4-dimethylphenyl)piperazin-1-yl)acetamide CAS 477333-96-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(3-chloro-4-methylphenyl)-2-(4-(2,4-dimethylphenyl)piperazin-1-yl)acetamide.

N-(3-chloro-4-methylphenyl)-2-(4-(2,4-dimethylphenyl)piperazin-1-yl)acetamide (CAS 477333-96-3), molecular formula C21H26ClN3O and molecular weight 371.90 g/mol, is a CATO reference standard with documented purity and traceability.

N-(3-chloro-4-methylphenyl)-2-(4-(2,4-dimethylphenyl)piperazin-1-yl)acetamide (C21H26ClN3O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC21H26ClN3O
Molecular Weight371.90 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms3

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Why CATO?