1-(3-Nitrophenyl)-3-((4-(trifluoromethyl)phenyl)amino)propan-1-one CAS 477334-29-5
| CAS No. | 477334-29-5 |
| Molecular Formula | C16H13F3N2O3 |
| Molecular Weight | 338.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(3-Nitrophenyl)-3-((4-(trifluoromethyl)phenyl)amino)propan-1-one (CAS 477334-29-5), molecular formula C16H13F3N2O3 and molecular weight 338.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(3-Nitrophenyl)-3-((4-(trifluoromethyl)phenyl)amino)propan-1-one (C16H13F3N2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(3-Nitrophenyl)-3-((4-(trifluoromethyl)phenyl)amino)propan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H13F3N2O3 |
| Molecular Weight | 338.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Nitrophenyl Standards
- 3-(2-(4-Nitrophenyl)acetamido)benzene-1-sulfonyl fluoride (CAS 19160-18-0)
- 4-(2-(4-Nitrophenyl)acetamido)benzene-1-sulfonyl fluoride (CAS 19188-69-3)
- 4-(2-(3-Nitrophenyl)acetamido)benzene-1-sulfonyl fluoride (CAS 19235-18-8)
- 2-((1-(2-Nitrophenyl)-1H-pyrrol-2-yl)thio)-1-phenylethanone (CAS 112798-17-1)
- 2-(3-Nitrophenyl)-3-(piperazin-1-ylmethyl)imidazo[1,2-a]pyridine (CAS 727975-37-3)
- 2-(4-Nitrophenyl)-3-(piperazin-1-ylmethyl)imidazo[1,2-a]pyridine (CAS 728864-97-9)
- Methyl 2-(3-(4-nitrophenyl)thioureido)thiophene-3-carboxylate (CAS 338777-35-8)
- 2-((4-Methyl-5-(((3-nitrophenyl)amino)methyl)-4H-1,2,4-triazol-3-yl)thio)acetohydrazide (CAS 1119449-47-6)
Recommended Standards
- (5-((4-Fluorophenyl)sulfonyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methanol (CAS 318469-24-8)
- 2-(2-Nitroethyl)-N-(3-(trifluoromethyl)phenyl)benzamide (CAS 343372-64-5)
- (3Z)-4-(Dimethylamino)-1,1,1-trifluoro-3-(1-nitronaphthalen-2-yl)but-3-en-2-one (CAS 339100-24-2)
- 3-((5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl)sulfonyl)benzoic acid (CAS 62617-21-4)
- 3-Bromo-N-(2-chloro-4-methylphenyl)benzamide (CAS 851273-95-5)
- Methyl 2-[(3S)-3-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]benzoate (CAS 181139-72-0)
- 2-Ethyl-4-hydroxy-5-methylfuran-3(2H)-one (CAS 27538-10-9)
- 1-Methyl-1H-benzo[d]imidazole-2-carbohydrazide (CAS 78620-29-8)
- (6-Amino-2,3-difluorophenyl)acetic acid (CAS 887585-05-9)
- Ethyl 8-methyl-4-(pyrrolidin-1-yl)quinoline-3-carboxylate (CAS 478248-18-9)
- 4-Hydroxy-2-methylenebutanoic acid (CAS 24923-76-0)
- 2-(4-Chlorophenyl)-5,5-dimethyl-1,3,2-dioxaborinane (CAS 585524-80-7)
- 5-(morpholinomethyl)thiazol-2-amine (CAS 3008-62-6)
- Semaglutide impurity 64 (CAS CATO-C4X-222664)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com