(S)-2-Amino-4-((1-phenylethyl)amino)quinoline-3-carbonitrile CAS 477708-01-3

Purity 97%+In StockPharmaceutical Standards
CAS No.477708-01-3
Molecular FormulaC18H16N4
Molecular Weight288.35 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(S)-2-Amino-4-((1-phenylethyl)amino)quinoline-3-carbonitrile CAS 477708-01-3 chemical structure

Description

As a certified reference material (CRM), (S)-2-Amino-4-((1-phenylethyl)amino)quinoline-3-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

(S)-2-Amino-4-((1-phenylethyl)amino)quinoline-3-carbonitrile (CAS 477708-01-3) is a high-purity analytical reference standard with the molecular formula C18H16N4 and a molecular weight of 288.35 g/mol.

The molecular framework of (S)-2-Amino-4-((1-phenylethyl)amino)quinoline-3-carbonitrile (C18H16N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC18H16N4
Molecular Weight288.35 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms4

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