2-(3,5-Dimethylphenyl)-4-methyl-6-[1-(4-methylphenyl)-1H-pyrazol-4-yl]-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione CAS 477708-77-3
| CAS No. | 477708-77-3 |
| Molecular Formula | C22H21N5O2 |
| Molecular Weight | 387.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 387.43 g/mol gives 2-(3,5-Dimethylphenyl)-4-methyl-6-[1-(4-methylphenyl)-1H-pyrazol-4-yl]-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-(3,5-Dimethylphenyl)-4-methyl-6-[1-(4-methylphenyl)-1H-pyrazol-4-yl]-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione (CAS 477708-77-3), a certified reference material (molecular formula C22H21N5O2, MW 387.43 g/mol) for analytical method development and quality control.
The molecular framework of 2-(3,5-Dimethylphenyl)-4-methyl-6-[1-(4-methylphenyl)-1H-pyrazol-4-yl]-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione (C22H21N5O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H21N5O2 |
| Molecular Weight | 387.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 5 |
Related Dimethylphenyl Standards
- 6-(2,6-Dimethylphenyl)-2-(methylthio)pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-one (CAS 847950-97-4)
- N-(4-((4-(3,5-Dimethylphenyl)piperazin-1-yl)sulfonyl)phenyl)acetamide (CAS 853752-41-7)
- 2-((2,4-Dimethylphenyl)thio)-N-(3-fluoro-4-(4-methylpiperazin-1-yl)phenyl)acetamide (CAS 478260-47-8)
- 2,3-Dimethylphenyl 2-(4-chlorophenyl)quinoline-4-carboxylate (CAS 355433-66-8)
- N-(3,4-Dimethylphenyl)-2-(1,1-dioxidothiomorpholino)-3-phenylpropanamide (CAS 477889-90-0)
- 6-(N-(3,4-dimethylphenyl)-N-methylsulfamoyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 434907-98-9)
- N-(2,6-dimethylphenyl)-3-(4-fluoro-2-nitrophenoxy)thiophene-2-carboxamide (CAS 306977-56-0)
- 2-((5-(3,4-Dimethylphenyl)thieno[2,3-d]pyrimidin-4-yl)amino)-2-phenylacetamide (CAS 1280785-43-4)
Recommended Standards
- 2-(2-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)phenyl)acetic acid (CAS 882847-15-6)
- 2-(8-bromo-1-naphthyl)ethynyl-triisopropyl-silane (CAS 2454490-90-3)
- 2-((4-Butylphenoxy)amino)-7-hydroxyanthracene-9,10-dione (CAS 91777-08-1)
- 2-Fluoro-N-(2-methoxy-ethyl)-N-[5-(4-methoxy-phenyl)-[1,3,4]thiadiazol-2-yl]-benzamide (CAS 603074-10-8)
- Ethyl 4-(thiophene-3-carbonyl)benzoate (CAS 896618-52-3)
- 845781-37-5 5-(3,5-Dimethylphenyl)-3-methyl-5-oxovaleric acid DTXSID00374415 (CAS 845781-37-5)
- 4-(Cyclopropylmethoxy)butanoic acid (CAS 1019515-26-4)
- 1-(Difluoromethoxy)-4-fluoro-2-methylbenzene (CAS 1214378-64-9)
- Carvedilol -D-Glucuronide (CAS 114869-83-9)
- [2,4'-Bipyrimidin]-5-ylboronic acid (CAS 2225172-40-5)
- (2-Bromo-6-(difluoromethyl)-3-methoxypyridin-4-yl)methanol (CAS 1805165-52-9)
- 6-Bromo-2,3-dimethoxybenzyl alcohol, 97% (CAS 107290-27-7)
- 5-Methyl-2,5-diazaspiro[3.5]nonane (CAS 1780716-27-9)
- Tirzepatide Impurity 34 (CAS CATO-C4X-324034)
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