N-(4-methoxyphenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide CAS 477709-58-3
| CAS No. | 477709-58-3 |
| Molecular Formula | C13H12F3N3O2 |
| Molecular Weight | 299.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(4-methoxyphenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide (C13H12F3N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies N-(4-methoxyphenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 477709-58-3), a certified reference material (molecular formula C13H12F3N3O2, MW 299.25 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-(4-methoxyphenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H12F3N3O2 |
| Molecular Weight | 299.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- 4-({[(4-methoxyphenyl)methyl]amino}methylidene)-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-one (CAS 338975-72-7)
- 6-(4-Methoxyphenyl)-2-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazole (CAS 798573-42-9)
- 6-(2-(4-Methoxyphenyl)-2-oxoethyl)-3-methyl-3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one (CAS 1058197-32-2)
- N-(5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)-1-methyl-1H-pyrazole-5-carboxamide (CAS 1170637-38-3)
- N-(5-(3-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)-1-methyl-1H-pyrazole-3-carboxamide (CAS 1171793-11-5)
- N-(5-(2-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)-1-methyl-1H-pyrazole-5-carboxamide (CAS 1173038-62-4)
- 3-(4-Methoxyphenyl)-2-methyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 1204298-05-4)
- N-(4-Methoxyphenyl)-2-(3-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-2(3H)-yl)acetamide (CAS 1327502-51-1)
Recommended Standards
- N-(2-(5-Oxo-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl)phenyl)propionamide (CAS 212903-44-1)
- N2-Methyl-N4-phenyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine (CAS 296769-69-2)
- Methyl 1-Methyl-5-[4-(trifluoromethoxy)phenyl]pyrrole-2-carboxylate (CAS 2006276-88-4)
- Salmeterol Impurity 27 (CAS CATO-C4X-105027)
- Noemethadone HCl (CAS 847-84-7)
- N-Ethyl-2-(1-(quinolin-2-yl)ethylidene)hydrazinecarbothioamide (CAS 88324-33-8)
- 7a-(Trifluoromethyl)-8,9-dihydro-7H-pyrrolo[1,2-a]perimidin-10(7aH)-one (CAS 1186629-87-7)
- 2-Chloro-N-{4-[(5-methyl-1,2-oxazol-3-yl)sulfamoyl]phenyl}acetamide (CAS 156324-47-9)
- Atrasentan Impurity 89 (CAS 1059043-39-8)
- 5-chloroindane-1-carbonitrile (CAS 132205-76-6)
- tert-Butyl (2,3-dihydrobenzo[b][1,4]dioxin-5-yl)carbamate (CAS 1116136-19-6)
- 3-amino-4-(1,5-dimethyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carbonitrile (CAS 1020058-98-3)
- 1-(Pyrimidin-2-yl)-1H-pyrazol-5-amine (CAS 41625-44-9)
- Semaglutide impurity 26 (CAS CATO-C4X-222626)
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