Ethyl 2-[1-(2,4-difluorophenyl)-1H-pyrazol-5-yl]-3-phenylpropanoate CAS 477710-92-2
| CAS No. | 477710-92-2 |
| Molecular Formula | C20H18F2N2O2 |
| Molecular Weight | 356.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 2-[1-(2,4-difluorophenyl)-1H-pyrazol-5-yl]-3-phenylpropanoate is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ethyl 2-[1-(2,4-difluorophenyl)-1H-pyrazol-5-yl]-3-phenylpropanoate (CAS 477710-92-2), molecular formula C20H18F2N2O2 and molecular weight 356.37 g/mol, is a CATO reference standard with documented purity and traceability.
Ethyl 2-[1-(2,4-difluorophenyl)-1H-pyrazol-5-yl]-3-phenylpropanoate (C20H18F2N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 2-[1-(2,4-difluorophenyl)-1H-pyrazol-5-yl]-3-phenylpropanoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H18F2N2O2 |
| Molecular Weight | 356.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Ethyl Standards
- 1-(2,4-Difluorophenyl)-3-(4-isobutylphenyl)-1H-pyrazole-5-carboxylic acid (CAS 618103-00-7)
- 2-((2,4-Difluorophenyl)sulfonyl)-1-(3,4-dimethoxyphenyl)ethan-1-one (CAS 1325304-65-1)
- 2-[(2,4-Difluorophenyl)carbamoyl]phenyl N,N-dimethylsulfamate (CAS 338396-32-0)
- 3-[(2,4-Difluorophenyl)carbamoyl]phenyl N,N-dimethylsulfamate (CAS 338405-84-8)
- 4-[(2,4-Difluorophenyl)carbamoyl]phenyl N,N-dimethylsulfamate (CAS 338396-19-3)
- 2-(2,6-Difluorophenyl)-1-[(2,6-Difluorophenyl)Methyl]Benzimidazole (CAS 199594-59-7)
- N-(2,5-difluorophenyl)-7-hydroxy-5-oxo-2,3-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-6-carboxamide (CAS 303987-25-9)
- 3-(2,6-Difluorophenyl)-4-[(2,6-dimethylmorpholin-4-yl)methyl]-2,3-dihydro-1,3-thiazole-2-thione (CAS 866153-89-1)
Recommended Standards
- Benzyl ((benzyloxy)carbonyl)-L-asparaginate (CAS 4668-39-7)
- Methyl (2E)-3-[(4-methoxyphenyl)amino]-2-[(4-methoxyphenyl)formamido]prop-2-enoate (CAS 245039-22-9)
- Benzoyl-L-tyrosyl-L-alanine (CAS 76264-09-0)
- Methyl 2-(4-hydroxy-1-(2-(5-methoxy-1H-indol-3-yl)ethyl)-2-oxo-1,2-dihydropyridin-3-yl)acetate (CAS 860612-56-2)
- (S)-1-((S)-tert-Butylsulfinyl)-2-(4-fluorophenyl)pyrrolidine (CAS 1218989-54-8)
- rel-1-(tert-butyl) 2-ethyl (2R,3R)-3-hydroxypiperidine-1,2-dicarboxylate (CAS 1135059-30-1)
- 2-Acetamido-3-(methylamino)propanoic acid (CAS 119945-11-8)
- Methyl (2S,3R)-3-Benzamido-2-hydroxy-3-phenylpropanoate (CAS 135821-94-2)
- 4-(2,2-Difluoroethoxy)benzenesulfonamide (CAS 1183965-30-1)
- tert-Butyl (2-(5-cyano-1H-indol-3-yl)ethyl)carbamate (CAS 144035-34-7)
- 3-Cyclopropoxy-2-nitroisonicotinamide (CAS 1243383-85-8)
- 6-Methoxy-1,2,3,4-tetrahydroisoquinolin-5-ol hydrochloride (CAS 1628638-77-6)
- (R)-1-(2,5-Dioxoimidazolidin-4-yl)urea (CAS 7303-80-2)
- C-Peptide（dog） (CAS 39016-05-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com