(Z)-3-[5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-2-(3,4-dichlorophenyl)-2-propenenitrile CAS 477762-21-3
| CAS No. | 477762-21-3 |
| Molecular Formula | C14H7Cl3F3N3 |
| Molecular Weight | 380.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (Z)-3-[5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-2-(3,4-dichlorophenyl)-2-propenenitrile.
CATO supplies (Z)-3-[5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-2-(3,4-dichlorophenyl)-2-propenenitrile (CAS 477762-21-3), a certified reference material (molecular formula C14H7Cl3F3N3, MW 380.58 g/mol) for analytical method development and quality control.
The molecular framework of (Z)-3-[5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-2-(3,4-dichlorophenyl)-2-propenenitrile (C14H7Cl3F3N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (Z)-3-[5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-2-(3,4-dichlorophenyl)-2-propenenitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H7Cl3F3N3 |
| Molecular Weight | 380.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Z Standards
- 4-chloro-6-[(4,5-dichloro-1H-imidazol-1-yl)methyl]-2-(trifluoromethyl)quinoline (CAS 662138-56-9)
- Methyl 4-chloro-2-iodo-1-(methoxymethyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxylate (CAS 1312581-07-9)
- 2-(2-Chloro-6-(ethoxymethoxy)-4-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2557357-85-2)
- 6-Chloro-3-iodo-1-(tetrahydro-2H-pyran-2-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS 2409582-17-6)
- 2-(4-Chloro-2-methylphenoxy)-N-(2,4-dichlorophenyl)-2,2-difluoroacetamide (CAS 339010-94-5)
- 2-Chloro-1H,1H-perfluorooct-1-ene (CAS 261503-26-8)
- 4-Chloro-3-(2,5-dichloro-phenylsulfamoyl)-benzoic acid (CAS 327092-97-7)
- 7-Chloro-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptanoic acid (CAS 1550-24-9)
Recommended Standards
- 3-(4-Bromophenyl)-5-(2-chloro-5-nitrophenyl)-1,2,4-oxadiazole (CAS 1707567-42-7)
- Thiol-C9-PEG5 (CAS 130727-42-3)
- Copper(II) phosphate (CAS 7798-23-4)
- Plerixafor Impurity 35 (CAS 214078-93-0)
- Suc-Phe-Pro-Phe-pNA (CAS 75651-68-2)
- (4-Nitrophenyl)(p-tolyl)sulfane (CAS 22865-48-1)
- 1-(2-Chlorophenoxy)-2-methylbenzene (CAS 68486-11-3)
- 4-((2-Methyl-3-nitrophenyl)amino)-4-oxobutanoic acid (CAS 304481-12-7)
- 3'-(3,4-Dichlorophenyl)-1-[(3,4-dichlorophenyl)methyl]-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione (CAS 338418-90-9)
- N1,N1-Dibutyl-N5-butylbiguanide hydrochloride (CAS 101491-45-6)
- Sodium 4-bromo-2-chlorobenzenesulfinate (CAS 1233505-70-8)
- Pregabalin Impurity 121 (CAS 959143-48-7)
- 5-Fluorobenzo[d]thiazole-2-carbonitrile (CAS 169776-03-8)
- Tyr-Proinsulin C-Peptide (55-89) (human) (CAS 139532-11-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com