8-[(Z)-2-[1-(4-Chlorophenyl)ethylidene]hydrazin-1-yl]quinoline hydrochloride CAS 477762-41-7
| CAS No. | 477762-41-7 |
| Molecular Formula | C17H15ClN3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-[(Z)-2-[1-(4-Chlorophenyl)ethylidene]hydrazin-1-yl]quinoline hydrochloride.
CATO supplies 8-[(Z)-2-[1-(4-Chlorophenyl)ethylidene]hydrazin-1-yl]quinoline hydrochloride (CAS 477762-41-7), a certified reference material (molecular formula C17H15ClN3Cl, MW 332.23 g/mol) for analytical method development and quality control.
8-[(Z)-2-[1-(4-Chlorophenyl)ethylidene]hydrazin-1-yl]quinoline hydrochloride (C17H15ClN3Cl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 8-[(Z)-2-[1-(4-Chlorophenyl)ethylidene]hydrazin-1-yl]quinoline hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H15ClN3 Cl |
| Molecular Weight | 332.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Z Standards
- 2-(2-Chlorophenyl)-2-(pyrrolidin-1-yl)acetamide (CAS 1000340-02-2)
- N-(2-Chlorophenyl)-5-methyl-1-phenyl-1H-1,2,4-triazole-3-carboxamide (CAS 1000572-01-9)
- N-(2-Chlorophenyl)-5-oxo-1-(p-tolyl)-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1000573-94-3)
- Methyl 1-(2-chlorophenyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazole-3-carboxylate (CAS 1000576-85-1)
- 1-(4-Chlorophenyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazole-3-carboxylic acid phenylamide (CAS 1000577-01-4)
- Benzyl 1-(4-chlorophenyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazole-3-carboxylate (CAS 1000577-09-2)
- 1-(2-Chlorophenyl)-5-oxo-N-phenyl-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1000577-29-6)
- 2-(2-Chlorophenyl)-1-phenylethan-1-amine (CAS 1000615-44-0)
Recommended Standards
- (3,4-Dichloro-2-fluorophenyl)methanol (CAS 1615212-17-3)
- 4-Methyl-3,5-diphenyl-4,5-dihydroisoxazol-5-ol (CAS 61184-64-3)
- (6-Amino-5-(difluoromethyl)-3-methylpyridin-2-yl)methanol (CAS 1805347-57-2)
- Methyl 2-amino-4-(4-(tert-butyl)phenyl)-5-methylthiophene-3-carboxylate (CAS 350990-39-5)
- ((3S,4R)-4-(2,5-difluorophenyl)pyrrolidin-3-yl)methanol (CAS 1186647-48-2)
- 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazolo[1,5-a]pyridine (CAS 1873385-99-9)
- Benzyl (cis-4-fluoropyrrolidin-3-yl)carbamate hydrochloride (CAS 1951441-41-0)
- 1-(Propan-2-yl)-1h-1,2,3-triazole-4-carboxylic acid (CAS 1249780-66-2)
- [4-(4-Bromo-Phenyl)-Tetrahydro-Pyran-4-Yl]-Methanol (CAS 894399-94-1)
- Semaglutide impurity 286 (CAS CATO-C4X-2226286)
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