(2-(tert-Butylcarbamoyl)-5-isobutylthiophen-3-yl)boronic acid CAS 477775-49-8

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2-(tert-Butylcarbamoyl)-5-isobutylthiophen-3-yl)boronic acid.

(2-(tert-Butylcarbamoyl)-5-isobutylthiophen-3-yl)boronic acid (CAS 477775-49-8) is a high-purity analytical reference standard with the molecular formula C13H22BNO3S and a molecular weight of 283.19 g/mol.

The molecular framework of (2-(tert-Butylcarbamoyl)-5-isobutylthiophen-3-yl)boronic acid (C13H22BNO3S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (2-(tert-Butylcarbamoyl)-5-isobutylthiophen-3-yl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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