6-[(2E)-3-[(4-Bromophenyl)amino]prop-2-enoyl]-2-(3,5-dimethylphenyl)-4-methyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione CAS 477845-37-7
| CAS No. | 477845-37-7 |
| Molecular Formula | C21H19BrN4O3 |
| Molecular Weight | 455.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 6-[(2E)-3-[(4-Bromophenyl)amino]prop-2-enoyl]-2-(3,5-dimethylphenyl)-4-methyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione (CAS 477845-37-7), a certified reference material (molecular formula C21H19BrN4O3, MW 455.30 g/mol) for analytical method development and quality control.
The molecular framework of 6-[(2E)-3-[(4-Bromophenyl)amino]prop-2-enoyl]-2-(3,5-dimethylphenyl)-4-methyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione (C21H19BrN4O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-[(2E)-3-[(4-Bromophenyl)amino]prop-2-enoyl]-2-(3,5-dimethylphenyl)-4-methyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H19BrN4O3 |
| Molecular Weight | 455.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
Related E Standards
- 3,5-Bis(3-bromophenyl)-4-phenyl-4H-1,2,4-triazole (CAS 1198843-27-4)
- 3,5-Bis(4-bromophenyl)-4-phenyl-4H-1,2,4-triazole (CAS 208124-25-8)
- 2-((4-Bromophenyl)sulfinyl)-N-(4-(2-chlorophenyl)thiazol-2-yl)acetamide (CAS 338965-84-7)
- 5-(Bromophenyl)-1,2,3,4,7,7-hexachloro-2-norbornene (CAS 36483-55-3)
- (Z)-[(4-Bromophenyl)[2-(4-chlorophenyl)cyclopropyl]methylidene]amino benzoate (CAS 338415-68-2)
- 2-((5-(2-Bromophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(5-chloro-2-methoxyphenyl)acetamide (CAS 332154-90-2)
- N-(4-Bromophenyl)-1-(2,4-dichloro-5-methoxyphenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide (CAS 339015-11-1)
- 1-(4-Bromophenyl)-3-(dodecylsulfanyl)pyrrolidine-2,5-dione (CAS 331461-21-3)
Recommended Standards
- 5-Bromo-2-(4-fluorophenyl)-N-methyl-6-(N-methylmethylsulfonamido)benzofuran-3-carboxamide (CAS 1333225-20-9)
- N,N-Bis(2-chloroethyl)-4-((2-(7-(trifluoromethyl)quinolin-4-yl)hydrazineylidene)methyl)aniline (CAS 91919-63-0)
- Ethyl (E)-2-(2-((3,5-dichlorophenyl)amino)vinyl)-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylate (CAS 240799-79-5)
- tert-Butyl (2,6-difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)biscarbamate (CAS 2377609-71-5)
- 2-(Thiophen-2-yl)quinoline (CAS 34243-33-9)
- (E)-6-(3-chlorostyryl)-4,4-dimethyl-2-(methylthio)-1,4-dihydropyrimidine (CAS 329234-81-3)
- 1,3-Dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carboxylic acid (CAS 64826-45-5)
- (R)-1-(Phenylcarbamoyl)pyrrolidine-2-carboxylic acid (CAS 827612-78-2)
- 1-(2-(Dimethylamino)-4-fluorophenyl)ethan-1-ol (CAS 1421602-01-8)
- 1-(5-(2-Methyl-1H-imidazol-1-yl)-2-nitrophenyl)-piperazine dihydrochloride (CAS 1177093-21-8)
- 2-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid (CAS 1060795-03-0)
- 1-((4-Methyl-4h-1,2,4-triazol-3-yl)thio)butan-2-amine (CAS 1343350-27-5)
- N'-(4-bromo-2-fluorobenzylidene)-4-methylbenzenesulfonohydrazide (CAS 2432855-08-6)
- Semaglutide impurity 206 (CAS CATO-C4X-2226206)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com