(E)-N'-[(2-Chloro-6-fluorophenyl)methoxy]-N-{thieno[2,3-d]pyrimidin-4-yl}methanimidamide CAS 477846-30-3
| CAS No. | 477846-30-3 |
| Molecular Formula | C14H10ClFN4OS |
| Molecular Weight | 336.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (E)-N'-[(2-Chloro-6-fluorophenyl)methoxy]-N-{thieno[2,3-d]pyrimidin-4-yl}methanimidamide (C14H10ClFN4OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
(E)-N'-[(2-Chloro-6-fluorophenyl)methoxy]-N-{thieno[2,3-d]pyrimidin-4-yl}methanimidamide (CAS 477846-30-3) is a high-purity analytical reference standard with the molecular formula C14H10ClFN4OS and a molecular weight of 336.77 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (E)-N'-[(2-Chloro-6-fluorophenyl)methoxy]-N-{thieno[2,3-d]pyrimidin-4-yl}methanimidamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H10ClFN4OS |
| Molecular Weight | 336.77 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Recommended Standards
- (3aR,4R,5R,6aS)-4-((E)-4-(3-Chlorophenoxy)-3-oxobut-1-en-1-yl)-5-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one (CAS 53872-62-1)
- (E)-N'-[(3-Chloro-2-fluorophenyl)methoxy]-N-{thieno[2,3-d]pyrimidin-4-yl}methanimidamide (CAS 477846-35-8)
- (2Z)-2-[(Z)-4-Chlorobenzoyl]-3-(5-methoxy-1H-indol-3-yl)prop-2-enenitrile (CAS 861207-67-2)
- 1-(3-((3-Chlorofuro[2,3-b]quinolin-4-yl)amino)phenyl)ethanone (CAS 629164-69-8)
- Methyl 1,3-dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyrimidine-6-carboxylate (CAS 501005-88-5)
- 4-((2,3,4-Trifluorophenoxy)methyl)benzaldehyde (CAS 1443353-74-9)
- 4,5-Dinitro-1H-imidazole (CAS 19183-14-3)
- 2-((2-(Methoxycarbonyl)phenyl)amino)acetic acid (CAS 64241-57-2)
- Dimethyl(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)phosphine oxide (CAS 2397623-67-3)
- 1-(2-Phenoxyacetyl)azetidine-3-carboxylic acid (CAS 1409888-63-6)
- Ethyl 3-ethyl-1,2,4-oxadiazole-5-carboxylate (CAS 139443-40-6)
- 3-Hydroxy-3-methylindolin-2-one (CAS 3040-34-4)
- 2-[1-(dimethylamino)-3-(4-phenoxyanilino)-2-propenylidene]malononitrile (CAS 338773-79-8)
- Semaglutide impurity 88 (CAS CATO-C4X-222688)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com