Methyl 5-((phenylmethyl)sulfonamido)benzo[b]thiophene-2-carboxylate CAS 477847-46-4
| CAS No. | 477847-46-4 |
| Molecular Formula | C17H15NO4S2 |
| Molecular Weight | 361.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methyl 5-((phenylmethyl)sulfonamido)benzo[b]thiophene-2-carboxylate is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Methyl 5-((phenylmethyl)sulfonamido)benzo[b]thiophene-2-carboxylate (CAS 477847-46-4) is a high-purity analytical reference standard with the molecular formula C17H15NO4S2 and a molecular weight of 361.44 g/mol.
The molecular framework of Methyl 5-((phenylmethyl)sulfonamido)benzo[b]thiophene-2-carboxylate (C17H15NO4S2) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 5-((phenylmethyl)sulfonamido)benzo[b]thiophene-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H15NO4S2 |
| Molecular Weight | 361.44 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
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Recommended Standards
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