2-{3-[4-Methyl-2-(2-pyridinyl)-1,3-thiazol-5-yl]-3-oxo-1-phenylpropyl}malononitrile CAS 477847-84-0
| CAS No. | 477847-84-0 |
| Molecular Formula | C21H16N4OS |
| Molecular Weight | 372.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, 2-{3-[4-Methyl-2-(2-pyridinyl)-1,3-thiazol-5-yl]-3-oxo-1-phenylpropyl}malononitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 372.44 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
2-{3-[4-Methyl-2-(2-pyridinyl)-1,3-thiazol-5-yl]-3-oxo-1-phenylpropyl}malononitrile (CAS 477847-84-0), molecular formula C21H16N4OS and molecular weight 372.44 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H16N4OS |
| Molecular Weight | 372.44 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- 3,6-Bis[2-(4-pyridinyl)ethenyl]-9H-carbazole (CAS 846042-18-0)
- 2,6-Bis[2-(2-pyridinyl)-5-oxazolyl]pyridine (CAS 1224193-58-1)
- 2-[2-(2-Pyridinyl)-5-oxazolyl]-6-[5-(2-pyridinyl)-2-oxazolyl]pyridine (CAS 1835305-09-3)
- Methyl 2-{[2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinyl]oxy}benzenecarboxylate (CAS 338754-17-9)
- 3-Phenyl-11-(3-pyridinyl)-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one (CAS 312626-57-6)
- 4-[4-(2-Pyridinyl)-2-pyrimidinyl]phenyl 2-phenylacetate (CAS 477857-40-2)
- 5-Oxo-5-[[6-[6-(2-pyridinyl)-1,2,4,5-tetrazin-3-yl]-3-pyridinyl]amino]pentanoic acid (CAS 1233234-76-8)
- 5-Methyl-2-(3-pyridinyl)-1,3-thiazol-4-yl 2,4-dichlorobenzenecarboxylate (CAS 338398-95-1)
Recommended Standards
- 2-(2,6-Dibromo-4-chloro-3,5-dimethylphenoxy)acetic acid (CAS 764710-09-0)
- 3-(3,4-Dimethoxyphenyl)-5-((3-methoxybenzyl)thio)-4H-1,2,4-triazol-4-amine (CAS 676623-46-4)
- 2-((4,5-Bis(4-methoxyphenyl)-1H-imidazol-2-yl)sulfinyl)ethanol (CAS 73181-83-6)
- 3-(3,4-Dimethoxyphenyl)-5-((4-methoxybenzyl)thio)-4H-1,2,4-triazol-4-amine (CAS 585553-48-6)
- 6-(2-methylsulfonylpyrimidin-5-yl)-N-prop-2-ynyl-hex-5-ynamide (CAS 2288710-39-2)
- (3R)-3-(propan-2-yloxy)pyrrolidine (CAS 1187932-43-9)
- Fmoc-Leu-OH (CAS 35661-60-0)
- 7-Chloro-3-methoxyquinoline (CAS 1965260-57-4)
- Methyl 2-butylpyrrolidine-1-carboxylate (CAS 131119-51-2)
- Cyclosporin H (CAS 83602-39-5)
- N-Boc-(+/-)-3-aminopent-4-en-(morpholin-4-yl)-amide (CAS 1379812-21-1)
- Methyl 2-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)benzoate (CAS 149989-77-5)
- 3-Butoxypyrrolidine hydrochloride (CAS 1211507-20-8)
- Adrenal Peptide E, bovine (CAS 78355-50-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com