(2E)-2-{[4-(trifluoromethyl)phenyl]methylidene}-1-azabicyclo[3.2.2]nonan-4-one CAS 477848-47-8
| CAS No. | 477848-47-8 |
| Molecular Formula | C16H16F3NO |
| Molecular Weight | 295.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(2E)-2-{[4-(trifluoromethyl)phenyl]methylidene}-1-azabicyclo[3.2.2]nonan-4-one (CAS 477848-47-8) is a high-purity analytical reference standard with the molecular formula C16H16F3NO and a molecular weight of 295.30 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, (2E)-2-{[4-(trifluoromethyl)phenyl]methylidene}-1-azabicyclo[3.2.2]nonan-4-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 295.30 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), (2E)-2-{[4-(trifluoromethyl)phenyl]methylidene}-1-azabicyclo[3.2.2]nonan-4-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H16F3NO |
| Molecular Weight | 295.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related E Standards
- 4-(3-(3-(Trifluoromethyl)phenyl)-1H-pyrazol-5-yl)piperidine (CAS 1030385-98-8)
- 3-Phenyl-3-(4-(trifluoromethyl)phenoxy)propan-1-amine (CAS 83891-03-6)
- 477848-10-5 2-{(E)-[2-(Trifluoromethyl)phenyl]methylidene}-1-azabicyclo[3.2.2]nonan-4-one MFCD02570750 (CAS 477848-10-5)
- 4-[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]phenol (CAS 880088-31-3)
- 5-Phenyl-7-(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-amine (CAS 850021-29-3)
- 4-(5-Trifluoromethyl-pyridin-2-yl)-benzoic acid ethyl ester (CAS 1089330-74-4)
- 2-(4-(Trifluoromethyl)phenyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(3H)-one (CAS 1355196-41-6)
- 2-(Methyl(3-(trifluoromethyl)phenyl)amino)benzoic acid (CAS 27696-34-0)
Recommended Standards
- 2-(benzylamino)-1-[2-(trifluoromethyl)phenyl]ethan-1-ol (CAS 1443980-61-7)
- 1-Allyl-2-imino-5-oxo-2,5-dihydro-1H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide (CAS 510761-21-4)
- N-(2-(1H-Pyrazol-1-yl)pyrimidin-5-yl)-2-phenoxyacetamide (CAS 1421526-84-2)
- 2-({4-[(difluoromethyl)sulfanyl]phenyl}amino)benzoic acid (CAS 51679-50-6)
- 5-Amino-1-(2-methoxyphenyl)-1H-1,2,3-triazole-4-carboxamide (CAS 443113-88-0)
- tert-Butyl ((1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-3-yl)methyl)(ethyl)carbamate (CAS 1354032-70-4)
- 5-Formyl-2-(methylsulfonyl)benzonitrile (CAS 1353878-08-6)
- 2-(2-Amino-6-(aminomethyl)-4-(difluoromethyl)pyridin-3-yl)acetonitrile (CAS 1805229-05-3)
- (E)-2-(Hex-1-en-1-yl)-5-methylfuran (CAS 861902-48-9)
- 4-((2,2-Dimethoxyethyl)amino)-2H-chromen-2-one (CAS 156742-55-1)
- Solifenacin Succinate (CAS 242478-38-2)
- 5-((tert-Butoxycarbonyl)amino)-4-oxopentanoic acid (CAS 72072-06-1)
- 2-(Oxetan-3-yl)phenol (CAS 1123786-81-1)
- [Tyr15] Fibrinopeptide B, human (CAS 125455-56-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com