N,2-bis(4-chlorophenyl)-1-oxo-1,2-dihydroisoquinoline-4-carboxamide CAS 477850-84-3
| CAS No. | 477850-84-3 |
| Molecular Formula | C22H14Cl2N2O2 |
| Molecular Weight | 409.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies N,2-bis(4-chlorophenyl)-1-oxo-1,2-dihydroisoquinoline-4-carboxamide (CAS 477850-84-3), a certified reference material (molecular formula C22H14Cl2N2O2, MW 409.26 g/mol) for analytical method development and quality control.
Structurally, N,2-bis(4-chlorophenyl)-1-oxo-1,2-dihydroisoquinoline-4-carboxamide (C22H14Cl2N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 409.26 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N,2-bis(4-chlorophenyl)-1-oxo-1,2-dihydroisoquinoline-4-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H14Cl2N2O2 |
| Molecular Weight | 409.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
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