(2E)-3-[(4-Chlorophenyl)amino]-2-(thiophen-3-yl)prop-2-enenitrile CAS 477851-21-1
| CAS No. | 477851-21-1 |
| Molecular Formula | C13H9ClN2S |
| Molecular Weight | 260.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (2E)-3-[(4-Chlorophenyl)amino]-2-(thiophen-3-yl)prop-2-enenitrile (CAS 477851-21-1), a certified reference material (molecular formula C13H9ClN2S, MW 260.74 g/mol) for analytical method development and quality control.
The molecular framework of (2E)-3-[(4-Chlorophenyl)amino]-2-(thiophen-3-yl)prop-2-enenitrile (C13H9ClN2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (2E)-3-[(4-Chlorophenyl)amino]-2-(thiophen-3-yl)prop-2-enenitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H9ClN2S |
| Molecular Weight | 260.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related E Standards
- 2-(3-Chlorophenyl)benzo[d]thiazol-6-amine (CAS 1267224-50-9)
- 1-(2-Chlorophenyl)-5-(thiophen-2-yl)-1H-pyrazole (CAS 1269291-36-2)
- 1-(2-Chlorophenyl)-5-(thiophen-3-yl)-1H-pyrazole (CAS 1269291-47-5)
- 1-(4-Chlorophenyl)-5-(thiophen-2-yl)-1H-pyrazole (CAS 1269294-00-9)
- 1-(3-Chlorophenyl)-5-(thiophen-2-yl)-1H-pyrazole (CAS 1269294-21-4)
- 1-((2-Chlorophenyl)sulfonyl)piperazine (CAS 233261-84-2)
- 1-(4-Chlorophenyl)-2-(propane-2-sulfonyl)ethan-1-one (CAS 344267-26-1)
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Recommended Standards
- 1-(4-Chloro-2,5-dimethoxyphenyl)-3-methylthiourea (CAS 196700-47-7)
- 4-(Benzo[d]thiazol-2-yl)-2-chloroaniline (CAS 178804-10-9)
- 1-((2-Chlorothiazol-5-yl)methyl)piperidine-4-carboxylic acid (CAS 939986-49-9)
- 2-Chloro-2-(methylsulfonyl)-1-(m-tolyl)propan-1-one (CAS 1707373-86-1)
- 2-Fluoro-4-(methylsulfonyl)benzonitrile (CAS 411233-40-4)
- 6-Bromo-3-iodo-1-methyl-1H-indazole (CAS 1260741-78-3)
- 4-Aminopyrido[2,3-d]pyrimidin-5(8H)-one (CAS 306960-30-5)
- 1-(Hydroxy(isopropyl)amino)-3-(naphthalen-1-yloxy)propan-2-ol (CAS 84418-31-5（free base）)
- 2,3-Dihydro-1h-inden-2-ylmethanamine hydrochloride (CAS 178955-07-2)
- [4-[(4-Methylpiperazin-1-yl)methyl]phenyl]boronic Acid (CAS 763120-62-3)
- Methyl 4-(chlorosulfonyl)-1-methyl-1H-pyrazole-5-carboxylate (CAS 1707586-97-7)
- Atomoxetine Impurity N15 (CAS 1643684-02-9)
- 1-Methyl-3-propoxy-1H-indazole-6-carbaldehyde (CAS 1987045-22-6)
- Palmitoyl Tripeptide-1 HCl (CAS 2757690-14-3)
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