7-(4-Methoxyphenoxy)-2,4-bis(trifluoromethyl)-1,8-naphthyridine CAS 477852-32-7
| CAS No. | 477852-32-7 |
| Molecular Formula | C17H10F6N2O2 |
| Molecular Weight | 388.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 388.26 g/mol gives 7-(4-Methoxyphenoxy)-2,4-bis(trifluoromethyl)-1,8-naphthyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
7-(4-Methoxyphenoxy)-2,4-bis(trifluoromethyl)-1,8-naphthyridine (CAS 477852-32-7), molecular formula C17H10F6N2O2 and molecular weight 388.26 g/mol, is a CATO reference standard with documented purity and traceability.
7-(4-Methoxyphenoxy)-2,4-bis(trifluoromethyl)-1,8-naphthyridine (C17H10F6N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 7-(4-Methoxyphenoxy)-2,4-bis(trifluoromethyl)-1,8-naphthyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H10F6N2O2 |
| Molecular Weight | 388.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Methoxyphenoxy Standards
- 7-(3-Methoxyphenoxy)-2,4-bis(trifluoromethyl)-1,8-naphthyridine (CAS 303996-17-0)
- 4-(4-Methoxyphenoxy)-2-(4-methylphenyl)-5-(piperidin-1-yl)-2,3-dihydropyridazin-3-one (CAS 478066-77-2)
- (Z)-2-(4-methoxyphenoxy)-N'-(2-phenoxynicotinoyl)acetohydrazonamide (CAS 303148-30-3)
- 2-(4-Methoxyphenoxy)-N-(4-((4-methylpiperazin-1-yl)methyl)phenyl)propanamide (CAS 1296786-90-7)
- 2-(4-Methoxyphenoxy)-4,6-dimethyl-3-(4-methylbenzenesulfonyl)pyridine (CAS 478245-34-0)
- 4-(4-Methoxyphenoxy)-2-(4-methylphenyl)-5-(morpholin-4-yl)-2,3-dihydropyridazin-3-one (CAS 478049-34-2)
- N-[4-(2-Methoxyphenoxy)phenylsulfonyl]-DL-leucine (CAS 1008647-74-2)
- 1-{[2-(4-methoxyphenoxy)-1,3-thiazol-5-yl]methyl}-4-phenylpiperazine (CAS 439097-05-9)
Recommended Standards
- Di-tert-butyl (4-bromopyridine-2,6-diyl)dicarbamate (CAS 410534-47-3)
- 5-((3-(Trifluoromethyl)phenoxy)methyl)-3-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole (CAS 860784-35-6)
- tert-Butyl(S)-3-(3-bromo-4-carbamoyl-5-(methylamino)-1h-pyrazol-1-yl)pyrrolidine-1-carboxylate (CAS 2173637-18-6)
- 4’-(4-Bromophenyl)-2,2’:6’,2’’-terpyridine (CAS 89972-76-9)
- Methyl 1-aminoisoquinoline-3-carboxylate (CAS 1203578-99-7)
- (4-(3-Methoxypropyl)-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride (CAS 1390654-53-1)
- 2-[4-(2-Fluorophenyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetonitrile (CAS 860784-78-7)
- 2-(Cyclopentylamino)-4-methylpentan-1-ol (CAS 1183790-72-8)
- (2-(Ethoxymethyl)phenyl)boronic acid (CAS 871329-56-5)
- 3-[5-(butylaminomethyl)-1-oxo-isoindolin-2-yl]piperidine-2,6-dione (CAS 2761170-95-8)
- N-Isopropyl-2-(2-methoxyphenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-amine (CAS 933021-16-0)
- (6-(2,2,2-Trifluoroethoxy)pyridazin-3-yl)methanamine (CAS 1250676-60-8)
- Methyl 4-chloro-5-formylpicolinate (CAS 1260664-17-2)
- Liraglutide Impurity 15 TFA Salt (CAS CATO-C4X-199215)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com