N'-((E)-(3-hydroxyisobenzofuran-1-yl)methylene)-N''-(4-methoxyphenyl)-2-nitroacetimidohydrazide CAS 477852-77-0
| CAS No. | 477852-77-0 |
| Molecular Formula | C18H16N4O5 |
| Molecular Weight | 368.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N'-((E)-(3-hydroxyisobenzofuran-1-yl)methylene)-N''-(4-methoxyphenyl)-2-nitroacetimidohydrazide.
CATO supplies N'-((E)-(3-hydroxyisobenzofuran-1-yl)methylene)-N''-(4-methoxyphenyl)-2-nitroacetimidohydrazide (CAS 477852-77-0), a certified reference material (molecular formula C18H16N4O5, MW 368.34 g/mol) for analytical method development and quality control.
Based on its molecular formula C18H16N4O5, N'-((E)-(3-hydroxyisobenzofuran-1-yl)methylene)-N''-(4-methoxyphenyl)-2-nitroacetimidohydrazide contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 368.34 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N'-((E)-(3-hydroxyisobenzofuran-1-yl)methylene)-N''-(4-methoxyphenyl)-2-nitroacetimidohydrazide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H16N4O5 |
| Molecular Weight | 368.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
Recommended Standards
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com