3-(4-Bromophenyl)-5-(2,4-dichlorophenoxy)-[1,2,4]triazolo[4,3-c]quinazoline CAS 477853-52-4
| CAS No. | 477853-52-4 |
| Molecular Formula | C21H11BrCl2N4O |
| Molecular Weight | 486.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(4-Bromophenyl)-5-(2,4-dichlorophenoxy)-[1,2,4]triazolo[4,3-c]quinazoline is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(4-Bromophenyl)-5-(2,4-dichlorophenoxy)-[1,2,4]triazolo[4,3-c]quinazoline (CAS 477853-52-4), molecular formula C21H11BrCl2N4O and molecular weight 486.15 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C21H11BrCl2N4O, 3-(4-Bromophenyl)-5-(2,4-dichlorophenoxy)-[1,2,4]triazolo[4,3-c]quinazoline contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 486.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H11BrCl2N4O |
| Molecular Weight | 486.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 4 |
Related Bromophenyl Standards
- 2-((4-Bromophenyl)sulfonyl)-1,1-bis(4-chlorophenyl)ethanol (CAS 303152-14-9)
- N-(3-Bromophenyl)-2-({3-methyl-4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-2-yl}sulfanyl)acetamide (CAS 1040634-02-3)
- N-(4-Bromophenyl)-2-({3-methyl-4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-2-yl}sulfanyl)acetamide (CAS 1040634-09-0)
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- 2-((1-Benzyl-5-(4-bromophenyl)-1H-imidazol-2-yl)thio)-N-(thiazol-2-yl)acetamide (CAS 1207023-09-3)
- 2-((2-(4-Bromophenyl)-2-oxoethyl)thio)-4,6-diphenylnicotinonitrile (CAS 297162-21-1)
- 7-(4-Bromophenyl)-2-(4-(2-fluorophenyl)piperazin-1-yl)thieno[3,2-d]pyrimidin-4(1H)-one (CAS 1242861-55-7)
- N-(4-((4-bromophenyl)sulfonyl)phenyl)-2,4-dichlorobenzamide (CAS 400088-86-0)
Recommended Standards
- 1H,1H,9H-Perfluorononyl acrylate (CAS 4180-26-1)
- Pseudouridine-5-triphosphate - 100mM aqueous solution (CAS 1175-34-4)
- 3,4-Dibromo-Mal-PEG2-N-Boc (CAS 1807537-43-4)
- Chlorantraniliprole-(<I>N-methyl</I>-d<SUB>3</SUB>) (CAS 1392493-28-5)
- 2-(Chloromethyl)-6-cyano-5-(difluoromethyl)-3-(trifluoromethyl)pyridine (CAS 1805038-21-4)
- 4-Amino-5-(trifluoromethyl)nicotinic acid (CAS 1806861-45-9)
- 2-(3-Ethoxy-4-hydroxyphenyl)acetic acid (CAS 80018-50-4)
- (4,5-Dihydrofuran-2-yl)(4,4-dimethylcyclopent-1-en-1-yl)methanone (CAS 649570-58-1)
- (S)-tert-Butyl (4-(2-amino-3-methylbutanamido)cyclohexyl)(cyclopropyl)carbamate (CAS 1353995-34-2)
- trans-1-((benzyloxy)carbonyl)-5-(trifluoromethyl)piperidine-3-carboxylic acid (CAS 1269757-31-4)
- 7-Benzyl-2,6-bis(methylthio)-7H-purine (CAS 92495-25-5)
- 3-(Methylamino)pyrazine-2-carboxylic acid (CAS 88394-07-4)
- 3-((3-Methylbenzyl)thio)-1-(m-tolyl)-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile (CAS 439107-41-2)
- ([D2]Gly4)-Cholecystokinin Octapeptide (sulfated) ammonium salt (CAS 1926163-74-7)
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