1-{2-[(3-chlorophenyl)sulfanyl]-4-methylquinolin-3-yl}ethan-1-one CAS 477854-47-0

Purity 97%+In StockPharmaceutical Standards
CAS No.477854-47-0
Molecular FormulaC18H14ClNOS
Molecular Weight327.83 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-{2-[(3-chlorophenyl)sulfanyl]-4-methylquinolin-3-yl}ethan-1-one CAS 477854-47-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 327.83 g/mol gives 1-{2-[(3-chlorophenyl)sulfanyl]-4-methylquinolin-3-yl}ethan-1-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1-{2-[(3-chlorophenyl)sulfanyl]-4-methylquinolin-3-yl}ethan-1-one (CAS 477854-47-0) is a high-purity analytical reference standard with the molecular formula C18H14ClNOS and a molecular weight of 327.83 g/mol.

1-{2-[(3-chlorophenyl)sulfanyl]-4-methylquinolin-3-yl}ethan-1-one (C18H14ClNOS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H14ClNOS
Molecular Weight327.83 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms1
Sulfur Atoms1

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