4-[(3-Methylphenyl)sulfanyl]-2-phenyl-5-pyrimidinecarboxylic acid CAS 477854-59-4
| CAS No. | 477854-59-4 |
| Molecular Formula | C18H14N2O2S |
| Molecular Weight | 322.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 4-[(3-Methylphenyl)sulfanyl]-2-phenyl-5-pyrimidinecarboxylic acid (CAS 477854-59-4), a certified reference material (molecular formula C18H14N2O2S, MW 322.38 g/mol) for analytical method development and quality control.
The molecular framework of 4-[(3-Methylphenyl)sulfanyl]-2-phenyl-5-pyrimidinecarboxylic acid (C18H14N2O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 4-[(3-Methylphenyl)sulfanyl]-2-phenyl-5-pyrimidinecarboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H14N2O2S |
| Molecular Weight | 322.38 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methylphenyl Standards
- 4-[(4-methylphenyl)methyl]-1-sulfanyl-4h,5h-[1,2,4]triazolo[4,3-a]quinazolin-5-one (CAS 722465-51-2)
- 4-[(4-Methylphenyl)sulfanyl]-2-phenylpyrimidine-5-carboxylic acid (CAS 477854-53-8)
- 4-[3-(4-Methylphenyl)-3-oxo-1-propenyl]phenyl pivalate (CAS 331460-43-6)
- N-(4-Methylphenyl)-3-nitro-4-(1H-1,2,4-triazol-1-yl)benzenecarboxamide (CAS 338407-90-2)
- 5-{[(2-methylphenyl)methyl]sulfanyl}-2H,3H-imidazo[1,2-c]quinazolin-2-one (CAS 478046-11-6)
- 5-{[(4-methylphenyl)methyl]sulfanyl}-2H,3H-imidazo[1,2-c]quinazolin-2-one (CAS 478046-22-9)
- 3-(3-Methylphenyl)-N-(4-methylphenyl)-2-(2H-1,2,3,4-tetrazol-5-yl)propanamide (CAS 483993-83-5)
- N-(2-Methylphenyl)-3-(3-methylphenyl)-2-(2H-1,2,3,4-tetrazol-5-yl)propanamide (CAS 483993-85-7)
Recommended Standards
- 4-(3,5-Dimethyl-phenyl)-1-mercapto-4H-[1,2,4]triazolo[4,3-a]quinazolin-5-one (CAS 565178-10-1)
- 4-(2,6-Dimethylphenyl)-1-sulfanyl-4h,5h-[1,2,4]triazolo[4,3-a]quinazolin-5-one (CAS 568570-14-9)
- 4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-pentylbenzenesulfonamide (CAS 61633-13-4)
- 4-Amino-N-(5-butoxypyrimidin-2-yl)benzenesulfonamide (CAS 93760-83-9)
- 5-Bromo-1,1,1-trifluoro-4-morpholinopent-3-en-2-one (CAS 790272-29-6)
- 4-Amino-2-(pyridin-4-yl)pyrimidine-5-carbonitrile (CAS 61310-40-5)
- 2-Hydroxyacetamide (CAS 598-42-5)
- Potassium trifluoro(1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-5-yl)borate (CAS 2739827-67-7)
- (2E)-1-(3-Bromophenyl)-3-(4-bromophenyl)prop-2-en-1-one (CAS 1674390-73-8)
- (2-Amino-5-ethylphenyl)boronic acid (CAS 948592-73-2)
- Methyl 3-(bromomethyl)-6-methylpyrazine-2-carboxylate (CAS 1260671-12-2)
- 6,7-Dihydro-5H-cyclopenta[b]pyridine-7-carbothioamide (CAS 69213-11-2)
- Gestodene Ketal (CAS 104933-99-5)
- Biotinyl-Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 1816258-36-2)
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