5-{[2-(Diethylamino)-1,3-thiazol-5-yl]methylene}-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione CAS 477855-05-3
| CAS No. | 477855-05-3 |
| Molecular Formula | C14H18N4O3S |
| Molecular Weight | 322.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-{[2-(Diethylamino)-1,3-thiazol-5-yl]methylene}-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione (CAS 477855-05-3) is a high-purity analytical reference standard with the molecular formula C14H18N4O3S and a molecular weight of 322.38 g/mol.
The molecular framework of 5-{[2-(Diethylamino)-1,3-thiazol-5-yl]methylene}-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione (C14H18N4O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 5-{[2-(Diethylamino)-1,3-thiazol-5-yl]methylene}-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H18N4O3S |
| Molecular Weight | 322.38 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Diethylamino Standards
- 4-(3-((Diethylamino)methyl)phenyl)-5-hydroxyisoquinolin-1(2H)-one (CAS 651029-61-7)
- 4-(4-((Diethylamino)methyl)phenyl)-5-hydroxyisoquinolin-1(2H)-one (CAS 651029-10-6)
- 7-(Diethylamino)-3-(4-methoxyphenyl)coumarin (CAS 720673-73-4)
- (2-(2-(Diethylamino)pyridin-3-yl)pyrrolidin-1-yl)(phenyl)methanone (CAS 1352484-71-9)
- 3-((Diethylamino)methyl)-5,5-diphenyldihydrofuran-2(3H)-one (CAS 99761-11-2)
- 2-(Diethylamino)ethyl 3-nitro-4-propoxybenzoate (CAS 736870-51-2)
- 2-(4-(Diethylamino)phenyl)-N-(1-phenylpropan-2-yl)acetamide (CAS 18464-55-6)
- 4,4＇-Bis(diethylamino)benzophenone (CAS 90-93-7)
Recommended Standards
- 5,7-Dibromo-4-chloroquinazoline (CAS 2021198-15-0)
- 5-Amino-N-(4-ethoxyphenyl)-2-methoxybenzene-1-sulfonamide (CAS 565194-84-5)
- 5-(Benzo[d]isoxazol-3-ylmethyl)-4-(p-tolyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 861206-87-3)
- 5-Oxo-2-(1H-pyrrol-1-yl)-4-(thiophen-2-yl)-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (CAS 477854-13-0)
- 3-(3-Phenylpropyl)azetidin-3-ol (CAS 1469100-10-4)
- 3-(2,2-Dimethylmorpholino)-N'-hydroxy-3-oxopropanimidamide (CAS 1158093-68-5)
- N-(4-chlorophenyl)-2,6-difluoro-3-nitrobenzamide (CAS 260442-70-4)
- 2-(tert-Butyl)benzo[d]oxazole-7-sulfonyl chloride (CAS 914638-40-7)
- 1-(2-Aminophenyl)piperidin-4-ol (CAS 252758-96-6)
- 3,4-Dimethyl-5-phenyl-4,5-dihydroisoxazol-5-ol (CAS 61184-63-2)
- 1-(Trifluoromethyl)trifluoroethanesultone (CAS 773-15-9)
- tert-Butyl (((S)-1-((S)-2-aminopropanoyl)pyrrolidin-2-yl)methyl)(methyl)carbamate (CAS 1401664-89-8)
- Fluconazole Impurity 39 (CAS CATO-C4X-101939)
- [14-31]-Semaglutide (CAS CATO-C4X-2226262)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com