N-{(E)-[2-(Diethylamino)-1,3-thiazol-5-yl]methylidene}isonicotinohydrazide CAS 477855-20-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-{(E)-[2-(Diethylamino)-1,3-thiazol-5-yl]methylidene}isonicotinohydrazide.

N-{(E)-[2-(Diethylamino)-1,3-thiazol-5-yl]methylidene}isonicotinohydrazide (CAS 477855-20-2), molecular formula C14H17N5OS and molecular weight 303.38 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of N-{(E)-[2-(Diethylamino)-1,3-thiazol-5-yl]methylidene}isonicotinohydrazide (C14H17N5OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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