4-Chloro-2-(2-(4-chlorophenyl)-2-oxoethyl)-5-(pyrrolidin-1-yl)pyridazin-3(2H)-one CAS 477855-92-8
| CAS No. | 477855-92-8 |
| Molecular Formula | C16H15Cl2N3O2 |
| Molecular Weight | 352.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-2-(2-(4-chlorophenyl)-2-oxoethyl)-5-(pyrrolidin-1-yl)pyridazin-3(2H)-one (C16H15Cl2N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 4-Chloro-2-(2-(4-chlorophenyl)-2-oxoethyl)-5-(pyrrolidin-1-yl)pyridazin-3(2H)-one (CAS 477855-92-8), a certified reference material (molecular formula C16H15Cl2N3O2, MW 352.22 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chloro-2-(2-(4-chlorophenyl)-2-oxoethyl)-5-(pyrrolidin-1-yl)pyridazin-3(2H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H15Cl2N3O2 |
| Molecular Weight | 352.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
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- 4-((4-Bromophenyl)(phenyl)amino)benzaldehyde (CAS 847978-62-5)
- tert-Butyl (7-bromo-2-methoxynaphthalen-1-yl)carbamate (CAS 2756522-44-6)
- 2-(2,5-Dimethoxyphenyl)-2-(pyrrolidin-1-yl)ethan-1-amine (CAS 928000-90-2)
- 3-(tert-Butyl)-4-cyclopropoxy-2-fluoropyridine (CAS 1243444-83-8)
- 4,4,5,5,6,6,6-Heptafluoro-1-(thiophen-2-yl)hexane-1,3-dione (CAS 559-94-4)
- 2,5-Bis(bromomethyl)cyclohexa-2,5-diene-1,4-dione (CAS 120475-64-1)
- 4-methoxy-3-(2-methoxyethoxy)aniline (CAS 26181-51-1)
- Ethyl 2-phenyl-4-(trifluoromethyl)pyrimidine-5-carboxylate (CAS 149771-11-9)
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