3-{[(4-fluorophenyl)sulfanyl]methyl}-2H,3H,5H-[1,3]thiazolo[2,3-b]quinazolin-5-one CAS 477855-97-3
| CAS No. | 477855-97-3 |
| Molecular Formula | C17H13FN2OS2 |
| Molecular Weight | 344.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-{[(4-fluorophenyl)sulfanyl]methyl}-2H,3H,5H-[1,3]thiazolo[2,3-b]quinazolin-5-one.
CATO supplies 3-{[(4-fluorophenyl)sulfanyl]methyl}-2H,3H,5H-[1,3]thiazolo[2,3-b]quinazolin-5-one (CAS 477855-97-3), a certified reference material (molecular formula C17H13FN2OS2, MW 344.43 g/mol) for analytical method development and quality control.
Based on its molecular formula C17H13FN2OS2, 3-{[(4-fluorophenyl)sulfanyl]methyl}-2H,3H,5H-[1,3]thiazolo[2,3-b]quinazolin-5-one contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 344.43 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-{[(4-fluorophenyl)sulfanyl]methyl}-2H,3H,5H-[1,3]thiazolo[2,3-b]quinazolin-5-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H13FN2OS2 |
| Molecular Weight | 344.43 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related fluorophenyl Standards
- 2-[(4-Fluorophenyl)sulfanyl]-N-(4-phenyl-1,3-thiazol-2-yl)acetamide (CAS 338957-83-8)
- 3-(2-Fluorophenyl)-4-((4-(methylthio)benzylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 578720-77-1)
- 3-(4-Fluorophenyl)-4-((4-(methylthio)benzylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 764655-45-0)
- N-(4-(4-fluorophenyl)thiazol-2-yl)-2-(phenylthio)acetamide (CAS 338957-71-4)
- N′-[3-(3-fluorophenyl)-2-(2-oxo-1-imidazolidinyl)propyl]-N,N-dimethylsulfamide (CAS 1421458-72-1)
- 3-(2-Fluorophenyl)-1-(furan-3-ylmethyl)-1-(2-(thiophen-2-yl)ethyl)urea (CAS 1421515-17-4)
- 4-(3-Fluorophenyl)-2,2-dimethyl-5-(4-(methylsulfinyl)phenyl)furan-3(2H)-one (CAS 301693-70-9)
- 1-(2-Fluorophenyl)-3-(2-((5-(pyrrolidin-1-yl)pyridazin-3-yl)amino)ethyl)urea (CAS 1796964-28-7)
Recommended Standards
- 3,5,5-Triphenyl-2-thioxoimidazolidin-4-one (CAS 52460-98-7)
- 3-Methyl-7-(3-methylbenzyl)-8-(propylthio)-3,7-dihydro-1H-purine-2,6-dione (CAS 303973-40-2)
- 3-(5-(Benzylthio)-4-phenyl-4H-1,2,4-triazol-3-yl)pyridine (CAS 500119-14-2)
- 3-Oxo-2-(thiophen-2-ylmethyl)isoindolin-1-yl tert-butylcarbamate (CAS 866008-23-3)
- Glutathione-(glycine- (CAS 815610-65-2)
- 3-Benzyl-3,6-diazabicyclo[3.2.2]nonane (CAS 1373273-51-8)
- 3-[5-(1H-Pyrazol-5-yl)-1,3-thiazol-2-yl]pyridine (CAS 1397189-42-2)
- 1,3,5-Trimethyl-4-(tributylstannyl)-1H-pyrazole (CAS 387353-98-2)
- Methyl 2,2-diethylthiazolidine-4-carboxylate (CAS 1437311-92-6)
- 5-chloro-2-methylquinaZolin-4(3h)-one (CAS 19407-56-8)
- n-(1-(3-Chlorophenyl)propyl)cyclopropanamine (CAS 954567-35-2)
- 4,6-Dimethylbenzo[d]isoxazol-3-amine (CAS 1344702-40-4)
- N-benzyl-N-(2-bromoethyl)methanesulfonamide (CAS 132552-89-7)
- (Des-Thr7)-Glucagon trifluoroacetate salt (CAS 1802078-28-9)
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