7-Chloro-N-(4-fluorophenyl)quinazolin-4-amine CAS 477856-23-8
| CAS No. | 477856-23-8 |
| Molecular Formula | C14H9ClFN3 |
| Molecular Weight | 273.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
7-Chloro-N-(4-fluorophenyl)quinazolin-4-amine (C14H9ClFN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 7-Chloro-N-(4-fluorophenyl)quinazolin-4-amine (CAS 477856-23-8), a certified reference material (molecular formula C14H9ClFN3, MW 273.69 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 7-Chloro-N-(4-fluorophenyl)quinazolin-4-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H9ClFN3 |
| Molecular Weight | 273.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- 7-Chloro-N-(3-fluorophenyl)quinazolin-4-amine (CAS 477856-40-9)
- Ethyl n-(2-chloroacetyl)-n-(4-fluorophenyl)glycinate (CAS 60145-88-2)
- 7-Chloro-8-fluoro-2-phenylquinolin-4(1H)-one (CAS 867165-00-2)
- Methyl 3-(2-chloroacetamido)-3-(3-fluorophenyl)propanoate (CAS 866144-58-3)
- 6-Bromo-1,3-dimethylquinoxalin-2(1H)-one (CAS 872188-46-0)
- 3-Cyclopropyl-1-[(2,6-dichlorophenyl)methyl]-1H-pyrazole (CAS 956780-00-0)
- 1-(1-Ethyl-1h-pyrazol-3-yl)ethan-1-amine (CAS 911788-34-6)
- N-[3-(Trifluoromethyl)phenyl]-2,3-dihydro-4H-1,4-benzothiazine-4-carboxamide (CAS 338750-69-9)
- (5E,7Z)-Dodeca-5,7-dien-1-ol (CAS 72922-18-0)
- 2-(4-Bromophenyl)-6-(thiophen-2-yl)-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 478068-09-6)
- N-(4-Ethynylphenyl)acetamide (CAS 35447-83-7)
- 5-Chloro-2,3-difluorobenzonitrile (CAS 1624261-31-9)
- 4-(Bromomethyl)-6-methoxy-1,2-difluorobenzene (CAS 887585-20-8)
- Semaglutide impurity 204 (CAS CATO-C4X-2226204)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com