7-Chloro-N-(2,4-dimethylphenyl)quinazolin-4-amine CAS 477856-35-2
| CAS No. | 477856-35-2 |
| Molecular Formula | C16H14ClN3 |
| Molecular Weight | 283.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-Chloro-N-(2,4-dimethylphenyl)quinazolin-4-amine.
7-Chloro-N-(2,4-dimethylphenyl)quinazolin-4-amine (CAS 477856-35-2), molecular formula C16H14ClN3 and molecular weight 283.76 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 7-Chloro-N-(2,4-dimethylphenyl)quinazolin-4-amine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 283.76 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H14ClN3 |
| Molecular Weight | 283.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 3-Chloro-4,5-bis(2-methylphenyl)-4h-1,2,4-triazole (CAS 1087784-52-8)
- 3-Chloro-7-methyl-1-phenyl-5,6,7,8-tetrahydro-2,7-naphthyridine-4-carbonitrile (CAS 1447960-16-8)
- 2-Chloro-6-methyl-4-phenyl-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carbonitrile (CAS 1708401-43-7)
- 2-Chloro-n-(1-phenylethyl)quinazolin-4-amine (CAS 597545-50-1)
- 2-Chloro-N-(4-methylbenzyl)quinazolin-4-amine (CAS 938524-71-1)
- 2-Chloro-N-methyl-N-(p-tolyl)quinazolin-4-amine (CAS 827030-34-2)
- 3-Chloro-7-(diallylamino)quinoline-8-carbonitrile (CAS 88347-07-3)
- 4-Chloro-6-methyl-5-(naphthalen-1-ylmethyl)pyrimidin-2-amine (CAS 500157-97-1)
Recommended Standards
- 7-Chloro-N-(2,3-dimethylphenyl)quinazolin-4-amine (CAS 477860-65-4)
- 7-Chloro-N-(2,5-dimethylphenyl)quinazolin-4-amine (CAS 477856-44-3)
- 5-(4-Chlorophenyl)-2,3,5,6-tetrahydroimidazo[1,2-c]quinazoline (CAS 23597-98-0)
- 7-Chloro-N-(2-methylbenzyl)quinazolin-4-amine (CAS 477861-95-3)
- Ethyl phenylsulfonylcarbamate (CAS 32111-09-4)
- Methyl 3-iodopropanoate (CAS 5029-66-3)
- Organophosphorus Pesticide Mix 12 (CAS CATO-MCPD101709-HE)
- N-{2-[2-(tert-Butyl)phenoxy]ethyl}-2-isobutoxyaniline (CAS 1040694-68-5)
- 4-Chloro-n-ethyl-2-fluorobenzenesulfonamide (CAS 863417-08-7)
- 4-tert-Butyl-1,3-oxazole (CAS 52713-54-9)
- 8-[[Tris(1-methylethyl)silyl]oxy]-1-octanol (CAS 234112-00-6)
- tert-Butyl 4-[cyano(phenyl)methyl]piperazine-1-carboxylate (CAS 444891-21-8)
- 4-Bromo-1-isobutyl-3-trifluoromethyl-1H-pyrazole (CAS 1437794-62-1)
- Semaglutide impurity 101 (CAS CATO-C4X-2226101)
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