2-{[(3-fluorophenyl)methyl]sulfanyl}-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazole CAS 477857-07-1
| CAS No. | 477857-07-1 |
| Molecular Formula | C16H10F4N2OS |
| Molecular Weight | 354.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-{[(3-fluorophenyl)methyl]sulfanyl}-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazole (C16H10F4N2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 2-{[(3-fluorophenyl)methyl]sulfanyl}-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazole (CAS 477857-07-1), a certified reference material (molecular formula C16H10F4N2OS, MW 354.32 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H10F4N2OS |
| Molecular Weight | 354.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related fluorophenyl Standards
- 4-(4-Fluorophenyl)-N-(4-(trifluoromethoxy)phenyl)thiazol-2-amine (CAS 497083-39-3)
- 7-(4-Fluorophenyl)-2-((3,4,4-trifluorobut-3-en-1-yl)thio)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 478043-72-0)
- N-(2-Fluorophenyl)-3-(5-(3-nitrophenyl)furan-2-yl)propanamide (CAS 853329-46-1)
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- 6-(4-Fluorophenyl)-2-((3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl)methyl)pyridazin-3(2H)-one (CAS 1105196-45-9)
- N-(2-Fluorophenyl)-3-(3-methylbutanamido)benzofuran-2-carboxamide (CAS 887875-15-2)
- 3-[5-(4-fluorophenyl)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid (CAS 1018150-56-5)
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Recommended Standards
- (S)-2-(5-Nitro-1H-indazole-1-carboxamido)-3-phenylpropanoic acid (CAS 664985-95-9)
- (3-Amino-6-methyl-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl)(4-fluorophenyl)methanone (CAS 354556-60-8)
- 7-Chloro-4-((2-chlorobenzyl)thio)-2,3-dihydrobenzo[b][1,4]thiazepine (CAS 303987-58-8)
- Methyl N-Boc-4-(trifluoroacetylamino)piperidine-4-carboxylate (CAS 1375064-57-5)
- 1-((Iodomethyl)sulfonyl)-4-methylbenzene (CAS 37891-96-6)
- (E)-N'-(6-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-3,5-dicyanopyridin-2-yl)-N,N-dimethylmethanimidamide (CAS 338794-98-2)
- 5'-Fluoro-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline] (CAS 1203682-87-4)
- 1-(2-Fluoroethyl)-1H-indol-5-ylamine (CAS 1508515-95-4)
- N-(furan-2-ylmethyl)-3,4,5-trimethoxybenzamide (CAS 60273-39-4)
- Apremilast impurity 128 (CAS 2489621-73-8)
- [1-(3-Fluorobenzyl)piperidin-4-yl]methylamine (CAS 893755-07-2)
- 3-Benzylamino-5,5-dimethyl-cyclohex-2-enone (CAS 889-31-6)
- PNU 159682 (CAS 202350-68-3)
- Semaglutide impurity 23 (CAS CATO-C4X-222623)
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