6,7-Dichloro-3-(trifluoromethyl)quinoxalin-2(1H)-one CAS 477857-25-3
| CAS No. | 477857-25-3 |
| Molecular Formula | C9H3Cl2F3N2O |
| Molecular Weight | 283.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6,7-Dichloro-3-(trifluoromethyl)quinoxalin-2(1H)-one (C9H3Cl2F3N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
6,7-Dichloro-3-(trifluoromethyl)quinoxalin-2(1H)-one (CAS 477857-25-3), molecular formula C9H3Cl2F3N2O and molecular weight 283.03 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6,7-Dichloro-3-(trifluoromethyl)quinoxalin-2(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H3Cl2F3N2O |
| Molecular Weight | 283.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloro Standards
- 2,4-Dichloro-7-(trifluoromethoxy)quinazoline (CAS 1160994-83-1)
- 2,3-Dichloro-6-(trifluoromethoxy)quinoxaline (CAS 1253522-03-0)
- 6,7-Dichloro-2-(trifluoromethyl)quinazolin-4(3H)-one (CAS 35982-56-0)
- 1,3-Dichloro-2,4-bis(trifluoromethyl)benzene (CAS 1221272-88-3)
- 1,2-Dichloro-4,5-bis(trifluoromethyl)benzene (CAS 320-22-9)
- 2,3-Dichloro-1,4-bis(trifluoromethyl)benzene (CAS 887268-06-6)
- 2,3-Dichloro-6-(difluoromethoxy)cinnamic acid (CAS 1807312-54-4)
- 2,4-Dichloro-6-(difluoromethoxy)cinnamic acid (CAS 1807312-80-6)
Recommended Standards
- Methyl 6-bromo-3-(difluoromethoxy)pyrazine-2-carboxylate (CAS 2812355-06-7)
- 2-Chloro-3,4,5,6-tetrafluorobenzene-1-sulfonyl chloride (CAS 2763570-72-3)
- Methyl 2-bromo-5-(trifluoromethyl)benzoate (CAS 1026355-57-6)
- 2-(Bromomethyl)-6-(difluoromethyl)-3-hydroxy-4-nitropyridine (CAS 1807123-74-5)
- 4-Bromo-5-methylthiazole-2-carbonitrile (CAS 2090046-28-7)
- 1-(3-((6-Chloropyridin-3-yl)methyl)piperidin-1-yl)ethan-1-one (CAS 1316223-57-0)
- 3-(Difluoromethyl)-5-hydroxy-2-oxo-1,2-dihydropyridine-4-carboxamide (CAS 1803667-84-6)
- 4-(Trifluoromethoxy)-2-(trifluoromethyl)-Benzenamine (CAS 409114-48-3)
- 2,6-Diaminonicotinic Acid (CAS 175155-53-0)
- Cyclopentyl(6-methylpyridin-2-yl)methanamine (CAS 1337625-07-6)
- 2-chloro-1,3-benzothiazol-7-amine (CAS 1782641-10-4)
- 6-tert-Butyldimethylsilyl-4'-hydroxy Raloxifene-d4 (CAS 1329611-25-7)
- Methyl 5-chloro-6-oxo-1,6-dihydropyridine-2-carboxylate (CAS 1214386-04-5)
- Lixisenatide (CAS 320367-13-3)
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