Methyl 3-(2-(2-oxo-2-((3-(trifluoromethyl)phenyl)amino)acetyl)-1H-pyrrol-1-yl)thiophene-2-carboxylate CAS 477857-77-5
| CAS No. | 477857-77-5 |
| Molecular Formula | C19H13F3N2O4S |
| Molecular Weight | 422.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Methyl 3-(2-(2-oxo-2-((3-(trifluoromethyl)phenyl)amino)acetyl)-1H-pyrrol-1-yl)thiophene-2-carboxylate (CAS 477857-77-5), a certified reference material (molecular formula C19H13F3N2O4S, MW 422.38 g/mol) for analytical method development and quality control.
The molecular framework of Methyl 3-(2-(2-oxo-2-((3-(trifluoromethyl)phenyl)amino)acetyl)-1H-pyrrol-1-yl)thiophene-2-carboxylate (C19H13F3N2O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C19H13F3N2O4S |
| Molecular Weight | 422.38 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Recommended Standards
- Methyl 3-(2-(2-oxo-2-((2-(trifluoromethyl)phenyl)amino)acetyl)-1H-pyrrol-1-yl)thiophene-2-carboxylate (CAS 477857-79-7)
- Methyl 3-[2-({[4-(trifluoromethyl)phenyl]carbamoyl}carbonyl)-1H-pyrrol-1-yl]thiophene-2-carboxylate (CAS 477857-78-6)
- Catechin-7-O-D-xylopyranoside (CAS 42830-48-8)
- O-(3-Cyano-6-(thiophen-2-yl)-4-(trifluoromethyl)pyridin-2-yl) O,O-diethyl phosphorothioate (CAS 286435-85-6)
- 2-(Azepan-1-yl)-N-(cyclopropylmethyl)ethan-1-amine (CAS 1184246-69-2)
- 2-Chloro-3-(difluoromethyl)-4-nitropyridine (CAS 1806760-97-3)
- 5-Methyl-1-(4-(methylthio)phenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1094373-30-4)
- 3-(Aminomethyl)pyrazine-2-carboxamide (CAS 98135-37-6)
- (<I>S</I>)[(<I>S</I><SUB>p</SUB>)-2-(diphenylphosphine)ferrocenyl]-4-isopropyloxane oxazoline (CAS 163169-29-7)
- (4-BORONOPHENYL)(PYRROLIDIN-1-YL)METHANONE 389621-81-2 4-BORONO-N-(1-PYRROLIDINYL)BENZAMIDE 4-PYRROLIDINYLCARBONYLPHENYLBORONIC ACID BC002043 BORONIC ACID, [4-(1-PYRROLIDINYLCARBONYL)PHENYL]- [4-(1-PYRROLIDINYLCARBONYL)PHENYL]-BORONIC ACID (CAS 389621-81-2)
- Ferrous gluconate dihydrate (CAS 6047-12-7)
- 2-((6-Phenylpyridazin-3-yl)oxy)ethan-1-amine (CAS 1283108-51-9)
- O-(4-(Phosphonooxy)benzyl) methanesulfonothioate (CAS 887407-33-2)
- Liraglutide-d8 Tetratrifluoroacetate (CAS 204656-20-2 (non-labelled, free base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com